Effect of α-tocopherol status on α-tocopherol transfer protein expression and its messenger RNA level in rat liver

Han Suk Kim, Hiroyuki Arai, Makoto Arita, Yuji Sato, Tohru Ogihara, Keizo Inoue, Makoto Mino, Hiroshi Tamai

研究成果: Article査読

35 被引用数 (Scopus)

抄録

Studies were designed to explore the role of vitamin E nutritional status in regulating the synthesis of α-tocopherol transfer protein (αTTP) in rat liver. In vitamin E-replete rats, expression of this protein and its specific messenger RNA (mRNA) was decreased by about 300% compared with rats with normal vitamin E levels. In vitamin E-depleted rats, the αTTP-specific mRNA level increased to about 150% of that in the normal vitamin E group. However, protein expression remained constant. These findings indicate that the synthesis of αTTP can be regulated by the vitamin E nutritional status.

本文言語English
ページ(範囲)87-92
ページ数6
ジャーナルFree Radical Research
28
1
出版ステータスPublished - 1998 4 23
外部発表はい

ASJC Scopus subject areas

  • 生化学

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