Effect of chronic exposure to acrylonitrile on subjective symptoms.

K. Kaneko, K. Omae

研究成果: Article

17 引用 (Scopus)

抄録

A cross-sectional study was performed to clarify the relationship between exposure to acrylonitrile (AN) and its effect on subjective symptoms by using a modified Cornell Medical Index (CMI) health questionnaire. The 7 acrylic fiber manufacturing factories surveyed were classified into 3 groups, namely, group L with a mean environmental acrylonitrile concentration of 1.8 ppm, group M with 7.4 ppm, and group H with 14.1 ppm. The total number of workers engaged in acrylic fiber manufacturing processes (acrylonitrile workers) and reference workers analyzed were 504 and 249, respectively. These consisted of 92 acrylonitrile workers and 108 reference workers in group L, 304 and 102 respectively in group M, and 108 and 39 respectively in group H. The mean values for length of exposure to acrylonitrile were 5.6 years in group L, 7.0 years in group M, and 8.6 years in group H. Neurotic status as determined by Fukamachi's criteria and Cornell Medical Index profiles did not show any AN-related differences between AN workers and reference workers in any of the groups. The subjective symptoms with significantly high prevalences in AN workers were "headache", "tongue trouble", "choking lump in throat", "fatigability", "general malaise", "heavy arms", and "heavy sweating". Except for "choking lump in throat" there was no relationship between the prevalence of symptoms and the length or level of exposure to acrylonitrile. These results suggested that long-term exposure to acrylonitrile at levels up to 14.1 ppm did not induce neurotic effects in acrylonitrile workers, but might cause some reversible subjective symptoms.

元の言語English
ページ(範囲)25-32
ページ数8
ジャーナルKeio Journal of Medicine
41
発行部数1
出版物ステータスPublished - 1992 3

Fingerprint

Acrylonitrile
Cornell Medical Index
Airway Obstruction
Pharynx
Sweating
Tongue
Headache
Arm
Cross-Sectional Studies

ASJC Scopus subject areas

  • Medicine(all)

これを引用

Effect of chronic exposure to acrylonitrile on subjective symptoms. / Kaneko, K.; Omae, K.

:: Keio Journal of Medicine, 巻 41, 番号 1, 03.1992, p. 25-32.

研究成果: Article

Kaneko, K & Omae, K 1992, 'Effect of chronic exposure to acrylonitrile on subjective symptoms.', Keio Journal of Medicine, 巻. 41, 番号 1, pp. 25-32.
Kaneko, K. ; Omae, K. / Effect of chronic exposure to acrylonitrile on subjective symptoms. :: Keio Journal of Medicine. 1992 ; 巻 41, 番号 1. pp. 25-32.
@article{2e15dd06b4854d9dafe25894620016e6,
title = "Effect of chronic exposure to acrylonitrile on subjective symptoms.",
abstract = "A cross-sectional study was performed to clarify the relationship between exposure to acrylonitrile (AN) and its effect on subjective symptoms by using a modified Cornell Medical Index (CMI) health questionnaire. The 7 acrylic fiber manufacturing factories surveyed were classified into 3 groups, namely, group L with a mean environmental acrylonitrile concentration of 1.8 ppm, group M with 7.4 ppm, and group H with 14.1 ppm. The total number of workers engaged in acrylic fiber manufacturing processes (acrylonitrile workers) and reference workers analyzed were 504 and 249, respectively. These consisted of 92 acrylonitrile workers and 108 reference workers in group L, 304 and 102 respectively in group M, and 108 and 39 respectively in group H. The mean values for length of exposure to acrylonitrile were 5.6 years in group L, 7.0 years in group M, and 8.6 years in group H. Neurotic status as determined by Fukamachi's criteria and Cornell Medical Index profiles did not show any AN-related differences between AN workers and reference workers in any of the groups. The subjective symptoms with significantly high prevalences in AN workers were {"}headache{"}, {"}tongue trouble{"}, {"}choking lump in throat{"}, {"}fatigability{"}, {"}general malaise{"}, {"}heavy arms{"}, and {"}heavy sweating{"}. Except for {"}choking lump in throat{"} there was no relationship between the prevalence of symptoms and the length or level of exposure to acrylonitrile. These results suggested that long-term exposure to acrylonitrile at levels up to 14.1 ppm did not induce neurotic effects in acrylonitrile workers, but might cause some reversible subjective symptoms.",
author = "K. Kaneko and K. Omae",
year = "1992",
month = "3",
language = "English",
volume = "41",
pages = "25--32",
journal = "Keio Journal of Medicine",
issn = "0022-9717",
publisher = "Keio University School of Medicine",
number = "1",

}

TY - JOUR

T1 - Effect of chronic exposure to acrylonitrile on subjective symptoms.

AU - Kaneko, K.

AU - Omae, K.

PY - 1992/3

Y1 - 1992/3

N2 - A cross-sectional study was performed to clarify the relationship between exposure to acrylonitrile (AN) and its effect on subjective symptoms by using a modified Cornell Medical Index (CMI) health questionnaire. The 7 acrylic fiber manufacturing factories surveyed were classified into 3 groups, namely, group L with a mean environmental acrylonitrile concentration of 1.8 ppm, group M with 7.4 ppm, and group H with 14.1 ppm. The total number of workers engaged in acrylic fiber manufacturing processes (acrylonitrile workers) and reference workers analyzed were 504 and 249, respectively. These consisted of 92 acrylonitrile workers and 108 reference workers in group L, 304 and 102 respectively in group M, and 108 and 39 respectively in group H. The mean values for length of exposure to acrylonitrile were 5.6 years in group L, 7.0 years in group M, and 8.6 years in group H. Neurotic status as determined by Fukamachi's criteria and Cornell Medical Index profiles did not show any AN-related differences between AN workers and reference workers in any of the groups. The subjective symptoms with significantly high prevalences in AN workers were "headache", "tongue trouble", "choking lump in throat", "fatigability", "general malaise", "heavy arms", and "heavy sweating". Except for "choking lump in throat" there was no relationship between the prevalence of symptoms and the length or level of exposure to acrylonitrile. These results suggested that long-term exposure to acrylonitrile at levels up to 14.1 ppm did not induce neurotic effects in acrylonitrile workers, but might cause some reversible subjective symptoms.

AB - A cross-sectional study was performed to clarify the relationship between exposure to acrylonitrile (AN) and its effect on subjective symptoms by using a modified Cornell Medical Index (CMI) health questionnaire. The 7 acrylic fiber manufacturing factories surveyed were classified into 3 groups, namely, group L with a mean environmental acrylonitrile concentration of 1.8 ppm, group M with 7.4 ppm, and group H with 14.1 ppm. The total number of workers engaged in acrylic fiber manufacturing processes (acrylonitrile workers) and reference workers analyzed were 504 and 249, respectively. These consisted of 92 acrylonitrile workers and 108 reference workers in group L, 304 and 102 respectively in group M, and 108 and 39 respectively in group H. The mean values for length of exposure to acrylonitrile were 5.6 years in group L, 7.0 years in group M, and 8.6 years in group H. Neurotic status as determined by Fukamachi's criteria and Cornell Medical Index profiles did not show any AN-related differences between AN workers and reference workers in any of the groups. The subjective symptoms with significantly high prevalences in AN workers were "headache", "tongue trouble", "choking lump in throat", "fatigability", "general malaise", "heavy arms", and "heavy sweating". Except for "choking lump in throat" there was no relationship between the prevalence of symptoms and the length or level of exposure to acrylonitrile. These results suggested that long-term exposure to acrylonitrile at levels up to 14.1 ppm did not induce neurotic effects in acrylonitrile workers, but might cause some reversible subjective symptoms.

UR - http://www.scopus.com/inward/record.url?scp=0026824269&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026824269&partnerID=8YFLogxK

M3 - Article

C2 - 1583816

AN - SCOPUS:0026824269

VL - 41

SP - 25

EP - 32

JO - Keio Journal of Medicine

JF - Keio Journal of Medicine

SN - 0022-9717

IS - 1

ER -