Effect of physician-prescribed nalmefene on alcohol intake reduction in patients with alcohol-related liver disease

研究成果: Article査読

抄録

A brief intervention is often effective for patients with mild alcohol use disorder (AUD), but it is not effective for most patients with severe AUD or alcohol dependence to reduce alcohol intake. Nalmefene (Selincro®), an opioid receptor modulator, was approved in Japan in 2019. Nalmefene was administered to 18 outpatients with alcohol-related liver diseases. Five patients stopped coming to the hospital without notice, and two patients stopped taking medicine due to dizziness. Thus, 11 patients were noted to have reduced amount of alcohol intake at 24 weeks of using nalmefene. However, one of these patients was referred to a hospital specializing in alcohol dependence thereafter. Thus, the use of nalmefene provides a new concept for AUD treatment (i. e., alcohol intake reduction). However, some adverse events are noted, such as nausea and dizziness. Therefore, physicians with more experience with AUD treatment should use the drugma.

本文言語English
ページ(範囲)620-629
ページ数10
ジャーナルActa Hepatologica Japonica
62
10
DOI
出版ステータスPublished - 2021

ASJC Scopus subject areas

  • 肝臓学

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「Effect of physician-prescribed nalmefene on alcohol intake reduction in patients with alcohol-related liver disease」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

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