Effect of repetitive stimulation on lateral spreads and F-waves in hemifacial spasm

Mami Ishikawa, Jun Namiki, Moriichiro Takase, Takayuki Ohira, Akiyoshi Nakamura, Shigeo Toya

研究成果: Article査読

28 被引用数 (Scopus)

抄録

The lateral spread (LS) response, which can be elicited in muscles innervated by other branches of the facial nerve, is electromyographically specific for patients with hemifacial spasm (HFS), occurring about 10 ms after stimulus. The F-wave in facial muscles, which is a late response that antidromicaly propagates to the facial motonucleus and returns orthodromicaly down the same axon, revealed a trend toward enhancement in patients with HFS. The LSs were facilitated by repetitive stimulation during the microvascular decompression (MVD) operation, which has proved to be a successful treatment, and the F-waves were also facilitated by repetitive stimulation on the spasm side more than on the normal side. Greater facilitation of these responses was in direct proportion to higher stimulation rates and greater numbers of stimulations. The repetitive stimulation of the facial nerve may result in activation of the motoneuron pool and in the lowering of the threshold of somatic membranes. These results support the hypothesis that hemifacial spasm is caused by hyperexcitability of the facial motonucleus, which is increased by antidromic repetitive stimulation.

本文言語English
ページ(範囲)99-106
ページ数8
ジャーナルJournal of the Neurological Sciences
142
1-2
DOI
出版ステータスPublished - 1996 10

ASJC Scopus subject areas

  • 神経学
  • 臨床神経学

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