TY - JOUR
T1 - Effectiveness of indocyanine green fluorescence in endoscopic marking in gastric cancer surgery
T2 - A feasibility study for replacing India ink
AU - Ono, Hiromi
AU - Kusano, Mitsuo
AU - Nihei, Masashi
AU - Hayashi, Hideyuki
AU - Fukushima, Hiraku
AU - Kawakami, Masato
AU - Danjo, Yasushi
AU - Nagashima, Kimimoto
AU - Shimizu, Yuichi
AU - Kawamata, Futoshi
AU - Honda, Shohei
AU - Shimamura, Tsuyoshi
AU - Nishihara, Hiroshi
N1 - Publisher Copyright:
© 2018 Japanese Society of Gastroenterology. All rights reserved.
PY - 2018
Y1 - 2018
N2 - When injected, indocyanine green (ICG) immediately combines with lipoproteins to fluoresce. Here, we studied whether ICG fluorescence is effective for endoscopic marking in gastric cancer surgery using a photodynamic eye (PDE) camera and fluorescent endoscope. An ICG solution was endoscopically injected into the submucosal layer of the gastric tumor 3 days before surgery. We observed the lesions using both a PDE camera and a fluorescent endoscope during laparotomy and laparoscopy, respectively; we also observed the fluorescent luminance and fluorescent size of the resected lesions. We could intraoperatively detect the size of the resected lesions in eight patients with early gastric cancer and six patients with advanced gastric cancer. We believe that the use of ICG fluorescence in endoscopic marking requires additional information, such as the volume of the ICG solution and the timing of the ICG injection.
AB - When injected, indocyanine green (ICG) immediately combines with lipoproteins to fluoresce. Here, we studied whether ICG fluorescence is effective for endoscopic marking in gastric cancer surgery using a photodynamic eye (PDE) camera and fluorescent endoscope. An ICG solution was endoscopically injected into the submucosal layer of the gastric tumor 3 days before surgery. We observed the lesions using both a PDE camera and a fluorescent endoscope during laparotomy and laparoscopy, respectively; we also observed the fluorescent luminance and fluorescent size of the resected lesions. We could intraoperatively detect the size of the resected lesions in eight patients with early gastric cancer and six patients with advanced gastric cancer. We believe that the use of ICG fluorescence in endoscopic marking requires additional information, such as the volume of the ICG solution and the timing of the ICG injection.
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U2 - 10.11405/nisshoshi.115.385
DO - 10.11405/nisshoshi.115.385
M3 - Article
C2 - 29643291
AN - SCOPUS:85046540086
SN - 0446-6586
VL - 115
SP - 385
EP - 393
JO - Journal of Japanese Society of Gastroenterology
JF - Journal of Japanese Society of Gastroenterology
IS - 4
ER -
