Effects of addition of early enteral nutritional support during the postoperative phase in patients after living-donor liver transplantation

Shigenori Ei, Masahiro Shinoda, Osamu Itano, Hideaki Obara, Minoru Kitago, Taizo Hibi, Hiroshi Yagi, Yuta Abe, Kentaro Matsubara, Yoshihiro Ono, Shigeyuki Kawachi, Ken Hoshino, Tatsuo Kuroda, Minoru Tanabe, Yuukou Kitagawa

研究成果: Article

5 引用 (Scopus)

抄録

Background: Early initiation of enteral nutrition is recommended after some surgical procedures. This study retrospectively analyzed the effects of addition of early enteral nutrition (EEN) support during the postoperative phase in patients after living-donor liver transplantation (LDLT). Material And Methods: The subjects were adult patients who underwent LDLT in our department and received either total parenteral nutrition (TPN) or EEN for postoperative nutritional support. We retrospectively compared clinical parameters between the TPN group (n=50) and the EEN group (n=45). Results: There were no significant differences in preoperative demographic data between the EEN and TPN groups with the exception of the follow-up period after surgery. In the EEN group, EEN was provided uneventfully; the daily amount of enteral nutrition was 996±465 kcal on postoperative day 7. Central venous catheters were removed significantly earlier in the EEN group than in the TPN group (postoperative day 11±7 vs. 28±18). The postoperative C-reactive protein level and the incidence of bacterial infection were significantly lower in the EEN group than in the TPN group. The postoperative length of hospital stay was significantly shorter and 6-month survival was significantly higher in the EEN group than in the TPN group. A multivariate analysis indicated that EEN was a significant factor for both shorter hospital stay and 6-month survival. Conclusions: Our retrospective analyses suggest that introduction of EEN had a great impact on postoperative short-term outcomes of LDLT.

元の言語English
ページ(範囲)357-365
ページ数9
ジャーナルAnnals of Transplantation
20
DOI
出版物ステータスPublished - 2015 6 25

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Nutritional Support
Living Donors
Enteral Nutrition
Liver Transplantation
Small Intestine
Total Parenteral Nutrition
Length of Stay
Survival
Central Venous Catheters
Bacterial Infections
C-Reactive Protein
Multivariate Analysis

ASJC Scopus subject areas

  • Transplantation

これを引用

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title = "Effects of addition of early enteral nutritional support during the postoperative phase in patients after living-donor liver transplantation",
abstract = "Background: Early initiation of enteral nutrition is recommended after some surgical procedures. This study retrospectively analyzed the effects of addition of early enteral nutrition (EEN) support during the postoperative phase in patients after living-donor liver transplantation (LDLT). Material And Methods: The subjects were adult patients who underwent LDLT in our department and received either total parenteral nutrition (TPN) or EEN for postoperative nutritional support. We retrospectively compared clinical parameters between the TPN group (n=50) and the EEN group (n=45). Results: There were no significant differences in preoperative demographic data between the EEN and TPN groups with the exception of the follow-up period after surgery. In the EEN group, EEN was provided uneventfully; the daily amount of enteral nutrition was 996±465 kcal on postoperative day 7. Central venous catheters were removed significantly earlier in the EEN group than in the TPN group (postoperative day 11±7 vs. 28±18). The postoperative C-reactive protein level and the incidence of bacterial infection were significantly lower in the EEN group than in the TPN group. The postoperative length of hospital stay was significantly shorter and 6-month survival was significantly higher in the EEN group than in the TPN group. A multivariate analysis indicated that EEN was a significant factor for both shorter hospital stay and 6-month survival. Conclusions: Our retrospective analyses suggest that introduction of EEN had a great impact on postoperative short-term outcomes of LDLT.",
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author = "Shigenori Ei and Masahiro Shinoda and Osamu Itano and Hideaki Obara and Minoru Kitago and Taizo Hibi and Hiroshi Yagi and Yuta Abe and Kentaro Matsubara and Yoshihiro Ono and Shigeyuki Kawachi and Ken Hoshino and Tatsuo Kuroda and Minoru Tanabe and Yuukou Kitagawa",
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TY - JOUR

T1 - Effects of addition of early enteral nutritional support during the postoperative phase in patients after living-donor liver transplantation

AU - Ei, Shigenori

AU - Shinoda, Masahiro

AU - Itano, Osamu

AU - Obara, Hideaki

AU - Kitago, Minoru

AU - Hibi, Taizo

AU - Yagi, Hiroshi

AU - Abe, Yuta

AU - Matsubara, Kentaro

AU - Ono, Yoshihiro

AU - Kawachi, Shigeyuki

AU - Hoshino, Ken

AU - Kuroda, Tatsuo

AU - Tanabe, Minoru

AU - Kitagawa, Yuukou

PY - 2015/6/25

Y1 - 2015/6/25

N2 - Background: Early initiation of enteral nutrition is recommended after some surgical procedures. This study retrospectively analyzed the effects of addition of early enteral nutrition (EEN) support during the postoperative phase in patients after living-donor liver transplantation (LDLT). Material And Methods: The subjects were adult patients who underwent LDLT in our department and received either total parenteral nutrition (TPN) or EEN for postoperative nutritional support. We retrospectively compared clinical parameters between the TPN group (n=50) and the EEN group (n=45). Results: There were no significant differences in preoperative demographic data between the EEN and TPN groups with the exception of the follow-up period after surgery. In the EEN group, EEN was provided uneventfully; the daily amount of enteral nutrition was 996±465 kcal on postoperative day 7. Central venous catheters were removed significantly earlier in the EEN group than in the TPN group (postoperative day 11±7 vs. 28±18). The postoperative C-reactive protein level and the incidence of bacterial infection were significantly lower in the EEN group than in the TPN group. The postoperative length of hospital stay was significantly shorter and 6-month survival was significantly higher in the EEN group than in the TPN group. A multivariate analysis indicated that EEN was a significant factor for both shorter hospital stay and 6-month survival. Conclusions: Our retrospective analyses suggest that introduction of EEN had a great impact on postoperative short-term outcomes of LDLT.

AB - Background: Early initiation of enteral nutrition is recommended after some surgical procedures. This study retrospectively analyzed the effects of addition of early enteral nutrition (EEN) support during the postoperative phase in patients after living-donor liver transplantation (LDLT). Material And Methods: The subjects were adult patients who underwent LDLT in our department and received either total parenteral nutrition (TPN) or EEN for postoperative nutritional support. We retrospectively compared clinical parameters between the TPN group (n=50) and the EEN group (n=45). Results: There were no significant differences in preoperative demographic data between the EEN and TPN groups with the exception of the follow-up period after surgery. In the EEN group, EEN was provided uneventfully; the daily amount of enteral nutrition was 996±465 kcal on postoperative day 7. Central venous catheters were removed significantly earlier in the EEN group than in the TPN group (postoperative day 11±7 vs. 28±18). The postoperative C-reactive protein level and the incidence of bacterial infection were significantly lower in the EEN group than in the TPN group. The postoperative length of hospital stay was significantly shorter and 6-month survival was significantly higher in the EEN group than in the TPN group. A multivariate analysis indicated that EEN was a significant factor for both shorter hospital stay and 6-month survival. Conclusions: Our retrospective analyses suggest that introduction of EEN had a great impact on postoperative short-term outcomes of LDLT.

KW - Bacterial infections and mycoses

KW - Enteral nutrition

KW - Length of stay

KW - Liver transplantation

KW - Survival

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U2 - 10.12659/AOT.893421

DO - 10.12659/AOT.893421

M3 - Article

C2 - 26108900

AN - SCOPUS:84933517281

VL - 20

SP - 357

EP - 365

JO - Annals of Transplantation

JF - Annals of Transplantation

SN - 1425-9524

ER -