抄録
The response of feline pial arteries to i.v. administration of isopropyl-(2-methoxyethyl)-1,4-dihydro-2,6-dimethyl 4-nitrophenyl-3,5-pyridinedicarboxylate (nimodipine, Bay e 9736) was studied by means of the vidicon camera system developed in our laboratory. Pial arteries showed a dose-dependent dilation with a reduction of systemic arterial blood pressure in the dose range of 0.001 mg/kg to 0.1 mg/kg of nimodipine. The dilatory response was more marked in the smaller arteries (< 100 μ) than in the larger ones (≥ 100μ).
| 本文言語 | English |
|---|---|
| ページ（範囲） | 1494-1497 |
| ページ数 | 4 |
| ジャーナル | Arzneimittel-Forschung/Drug Research |
| 巻 | 30 |
| 号 | 9 |
| 出版ステータス | Published - 1980 11 10 |
ASJC Scopus subject areas
- Drug Discovery