Efficacy of 18-FDG PET-CT dual-phase scanning for detection of lymph node metastasis in gynecological cancer

研究成果: Article査読

5 被引用数 (Scopus)

抄録

Aim: This study investigated whether dual-phase scanning (DPS) with 18-fludeoxyglucose positron emission tomography -computed tomography (FDG PET-CT) improves diagnosis of lymph node metastasis (LNM) in gynecologic malignancies, compared to mono-phase scanning (MPS). Patients and Methods: The study included 139 patients who underwent PET-CT followed by systemic lymph node dissection. PET-CT scans were obtained twice. The maximum standardized uptake value (SUVmax) was measured and the retention index (RI) was calculated as the % change from the early to the delayed scan. The optimal threshold of RI was determined using a receiver operating characteristic (ROC) curve. Diagnostic efficacies were calculated for MPS and DPS using pathological results. Results: In total, 1,879 regions were dissected. The optimal RI was 9%. The sensitivity, specificity and accuracy were 35.8%, 99.0% and 96.8% for MPS and 26.9%, 99.6% and 97.0% for DPS, respectively. Specificity was significantly improved by DPS and accuracy was also improved, but not significantly. Conclusion: DPS had an unsatisfactory impact on the diagnostic efficacy for LNM.

本文言語English
ページ(範囲)2247-2253
ページ数7
ジャーナルAnticancer research
35
4
出版ステータスPublished - 2015 4 1

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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