Efficient preparation of 4-hydroxyquinolin-2(1 H)-one derivatives with silver-catalyzed carbon dioxide incorporation and intramolecular rearrangement

Tomonobu Ishida, Satoshi Kikuchi, Tohru Yamada

研究成果: Article査読

82 被引用数 (Scopus)

抄録

Although 4-hydroxyquinolin-2(1H)-one derivatives have attracted much attention due to their biological benefits, conventional reactions under harsh heat conditions must be employed to provide these key compounds. In the presence of a catalytic amount of silver salt, various o-alkynylanilines were treated with carbon dioxide and a base under mild reaction conditions to afford the corresponding 4-hydroxyquinolin-2(1H)-one derivatives in high yield.

本文言語English
ページ(範囲)3710-3713
ページ数4
ジャーナルOrganic Letters
15
14
DOI
出版ステータスPublished - 2013 7 19

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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