Elevated levels of interleukin-8 and leukotriene B4 in pulmonary edema fluid of a patient with reexpansion pulmonary edema

Hidetoshi Nakamura, Akitoshi Ishizaka, Makoto Sawafuji, Tetsuya Urano, Seitaro Fujishima, Fumio Sakamaki, Koichi Sayama, Masafumi Kawamura, Ryoichi Kato, Koji Kikuchi, Minoru Kanazawa, Koichi Kobayashi, Takeo Kawashiro

研究成果: Article査読

56 被引用数 (Scopus)

抄録

We experienced a case of reexpansion pulmonary edema (RPE) after surgical treatment of pneumothorax. In this case, protein leakage and polymorphonuclear leukocyte (PMN) accumulation were observed in the reexpanded lung. Interleukin-8 and leukotriene B4 in edema fluid were increased at the onset of RPE. PMN elastase was also increased, though its peak was delayed. The plasma level of P-selectin, which mediates adhesion between PMN and endothelium, was elevated. We speculate that some of these fluid mediators may play important roles in chemotaxis and activation of PMN in the development of RPE.

本文言語English
ページ(範囲)1037-1040
ページ数4
ジャーナルAmerican journal of respiratory and critical care medicine
149
4
DOI
出版ステータスPublished - 1994 4

ASJC Scopus subject areas

  • 呼吸器内科
  • 集中医療医学

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