Enantioselective borohydride reduction of ketones catalyzed by optically active cobalt(II) complexes: Achievement of high enantioselection by modified borohydrides with furfuryl alcohol derivatives

Kiyoaki D. Sugi, Takushi Nagata, Tohru Yamada, Teruaki Mukaiyama

研究成果: Article査読

37 被引用数 (Scopus)

抄録

The enantioselective borohydride reduction of ketones catalyzed by optically active (β-oxoaldiminato) cobalt(II) complexes was remarkably improved by using the borohydride which was modified with furfuryl alcohol derivatives and ethanol. In the presence of 1 mol% of the above complex catalysts, asymmetric reduction of aromatic ketones proceeded smoothly to give the corresponding optically active alcohols in quantitative yields within 6-12 h with high enantiomeric excesses (90-97% ee).

本文言語English
ページ(範囲)737-738
ページ数2
ジャーナルChemistry Letters
9
DOI
出版ステータスPublished - 1996 1月 1
外部発表はい

ASJC Scopus subject areas

  • 化学 (全般)

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