TY - JOUR
T1 - Enantioselective transfer hydrogenation of difluoromethyl ketimines using benzothiazoline as a hydrogen donor in combination with a chiral phosphoric acid
AU - Sakamoto, Tsubasa
AU - Horiguchi, Kosaku
AU - Saito, Kodai
AU - Mori, Keiji
AU - Akiyama, Takahiko
PY - 2013/11
Y1 - 2013/11
N2 - Hold the benzothiazoline: Highly enantioselective transfer hydrogenation of difluoromethyl ketimines with benzothiazolines catalyzed by a chiral phosphoric acid furnishes α-difluoromethylated amines in good yields and with excellent enantioselectivity, irrespective of the stereochemistry of the starting materials. PMP=p-methoxyphenyl.
AB - Hold the benzothiazoline: Highly enantioselective transfer hydrogenation of difluoromethyl ketimines with benzothiazolines catalyzed by a chiral phosphoric acid furnishes α-difluoromethylated amines in good yields and with excellent enantioselectivity, irrespective of the stereochemistry of the starting materials. PMP=p-methoxyphenyl.
KW - Benzothiazolines
KW - Chiral phosphoric acids
KW - Difluoromethyl amines
KW - Difluoromethyl ketimines
KW - Enantioselective transfer hydrogenation
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U2 - 10.1002/ajoc.201300174
DO - 10.1002/ajoc.201300174
M3 - Article
AN - SCOPUS:84896751751
VL - 2
SP - 943
EP - 946
JO - Asian Journal of Organic Chemistry
JF - Asian Journal of Organic Chemistry
SN - 2193-5807
IS - 11
ER -