Enantioselective transfer hydrogenation of difluoromethyl ketimines using benzothiazoline as a hydrogen donor in combination with a chiral phosphoric acid

Tsubasa Sakamoto; Kosaku Horiguchi; Kodai Saito; Keiji Mori; Takahiko Akiyama

doi:10.1002/ajoc.201300174

Enantioselective transfer hydrogenation of difluoromethyl ketimines using benzothiazoline as a hydrogen donor in combination with a chiral phosphoric acid

Tsubasa Sakamoto, Kosaku Horiguchi, Kodai Saito, Keiji Mori, Takahiko Akiyama

研究成果: Article › 査読

13 被引用数 (Scopus)

抄録

Hold the benzothiazoline: Highly enantioselective transfer hydrogenation of difluoromethyl ketimines with benzothiazolines catalyzed by a chiral phosphoric acid furnishes α-difluoromethylated amines in good yields and with excellent enantioselectivity, irrespective of the stereochemistry of the starting materials. PMP=p-methoxyphenyl.

本文言語	English
ページ（範囲）	943-946
ページ数	4
ジャーナル	Asian Journal of Organic Chemistry
巻	2
号	11
DOI	https://doi.org/10.1002/ajoc.201300174
出版ステータス	Published - 2013 11
外部発表	はい

ASJC Scopus subject areas

Organic Chemistry

文献へのアクセス

10.1002/ajoc.201300174

フィンガープリント「Enantioselective transfer hydrogenation of difluoromethyl ketimines using benzothiazoline as a hydrogen donor in combination with a chiral phosphoric acid」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル

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abstract = "Hold the benzothiazoline: Highly enantioselective transfer hydrogenation of difluoromethyl ketimines with benzothiazolines catalyzed by a chiral phosphoric acid furnishes α-difluoromethylated amines in good yields and with excellent enantioselectivity, irrespective of the stereochemistry of the starting materials. PMP=p-methoxyphenyl.",

keywords = "Benzothiazolines, Chiral phosphoric acids, Difluoromethyl amines, Difluoromethyl ketimines, Enantioselective transfer hydrogenation",

author = "Tsubasa Sakamoto and Kosaku Horiguchi and Kodai Saito and Keiji Mori and Takahiko Akiyama",

year = "2013",

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AU - Horiguchi, Kosaku

AU - Saito, Kodai

AU - Mori, Keiji

AU - Akiyama, Takahiko

PY - 2013/11

Y1 - 2013/11

N2 - Hold the benzothiazoline: Highly enantioselective transfer hydrogenation of difluoromethyl ketimines with benzothiazolines catalyzed by a chiral phosphoric acid furnishes α-difluoromethylated amines in good yields and with excellent enantioselectivity, irrespective of the stereochemistry of the starting materials. PMP=p-methoxyphenyl.

AB - Hold the benzothiazoline: Highly enantioselective transfer hydrogenation of difluoromethyl ketimines with benzothiazolines catalyzed by a chiral phosphoric acid furnishes α-difluoromethylated amines in good yields and with excellent enantioselectivity, irrespective of the stereochemistry of the starting materials. PMP=p-methoxyphenyl.

KW - Benzothiazolines

KW - Chiral phosphoric acids

KW - Difluoromethyl amines

KW - Difluoromethyl ketimines

KW - Enantioselective transfer hydrogenation

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