Endosaccular embolization of an intrasellar aneurysm with hypopituitarism: Case report

Mutsumi Fujii, Osamu Tone, Hiroki Tomita, Masashi Tamaki, Hideaki Akimoto, Keigo Shigeta, Oltea Sampetrean, Kazuo Kanno, Mika Matsushita

研究成果: Article

3 引用 (Scopus)

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An 81-year-old male presented with weight loss and hyponatremia. A baseline endocrinological examination revealed anterior pituitary dysfunction. A computed tomography and MRI revealed a large, unruptured intrasellar aneurysm protruding from the right internal carotid artery and pushing the pituitary stalk leftward. The patient developed polyuria and polydipsia from 10 days after commencing corticosteroid supplementation and was diagnosed with partial central diabetes insipidus (DI). Balloon assisted endosaccular embolization was performed about one month after the posterior pituitary dysfunction was identified. The unruptured aneurysm was successfully embolized with Guglielmi detachable coils (GDCs) without narrowing of the parent vessel. DI resolved completely and the posterior pituitary dysfunction imploved soon after endosaccular embolization. The remission of DI after coil embolization suggested that the DI might have been induced by the progressive mass effect of the aneurysm rather than by the steroid. An endocrinological evaluation and cerebral angiography confirmed partial recovery of anterior pituitary dysfunction and almost complete obliteration of the aneurysm, respectively, at 1 year after the operation. We report a case of hypopituitarism secondary to the large intrasellar aneurysm. This aneurysm was embolized with GDCs, resulting in partial recovery of anterior pituitary dysfunction and complete recovery of posterior pituitary dysfunction.

元の言語English
ページ(範囲)329-337
ページ数9
ジャーナルNeurological Surgery
36
発行部数4
出版物ステータスPublished - 2008 4 1
外部発表Yes

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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    Fujii, M., Tone, O., Tomita, H., Tamaki, M., Akimoto, H., Shigeta, K., Sampetrean, O., Kanno, K., & Matsushita, M. (2008). Endosaccular embolization of an intrasellar aneurysm with hypopituitarism: Case report. Neurological Surgery, 36(4), 329-337.