We demonstrated that phototoxicity was enhanced by applying a single nanosecond-pulsed-laser-induced stress wave (LISW) to cultured cells before photodynamic treatment. Observation with a confocal laser scanning microscope showed that the enhanced phototoxicity is attributable to the larger cellular uptake of a photosensitizer due to the effect of LISW. It was also confirmed that the application of LISW alone did not reduce the cell viability.
|ジャーナル||Japanese Journal of Applied Physics, Part 2: Letters|
|出版ステータス||Published - 2004 7月 1|
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