Enhanced theophylline metabolism in patients with bronchial asthma at age 4 and under

Junko Kizu, Motoki Arakawa, Yoshihiro Arakawa, Fusako Komoda, Masaru Takamizawa, Tsutomu Iwata, Tetsuo Hayakawa, Kazuhiro Imai

研究成果: Article査読

1 被引用数 (Scopus)

抄録

The plasma levels of theophylline (TP) and its metabolites were measured in patients with bronchial asthma who were treated with a slow-release preparation of TP. The ratios of the plasma levels of these metabolites to TP levels in the group aged 1-4 years were larger than those in the group aged 5 years and older, suggesting enhanced activity of drug-metabolizing enzymes during infancy.

本文言語English
ページ(範囲)462-464
ページ数3
ジャーナルBiomedical Chromatography
13
7
DOI
出版ステータスPublished - 1999

ASJC Scopus subject areas

  • 分析化学
  • 生化学
  • 分子生物学
  • 薬理学
  • 創薬
  • 臨床生化学

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