Enzyme- and microorganism-mediated syntheses of substances related to glycoconjugates

Atsuhito Kuboki, Mikio Bakke, Takahiro Sekiguchi, Hiromichi Ohta, Takeshi Sugai

研究成果: Article査読

1 被引用数 (Scopus)

抄録

In this article, chemo-enzymatic syntheses of important substances which serve as the building blocks for glycoconjugate synthesis are described : 1) Sialic acid aldolase-catalyzed synthesis of sialic acids and its analogs ; 2) Studies on Rhodococcus rhodochrous IFO 15564-catalyzed degradation of N-acetyl-D-glucosamine and its derivatives ; 3) Hydration of carbohydrate nitriles mediated by a nitirle hydratase produced by R. rhodochrous IFO 15564 ; 4) Synthesis of N-acetyl-D-allosamine based on the lipase-catalyzed regioselective acetylation as the key step ; 5) Kinetic optical resolution of highly deoxygenated carbohydrate by means of lipase-catalyzed transesterification ; 6) Kinetic optical resolution of ceramide based on lipase-catalyzed hydrolysis.

本文言語English
ページ(範囲)489-499
ページ数11
ジャーナルYuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry
56
6
DOI
出版ステータスPublished - 1998 6

ASJC Scopus subject areas

  • 有機化学

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