Eosinophilic pustular folliculitis (Ofuji's disease): Indomethacin as a first choice of treatment

T. Ota, Y. Hata, A. Tanikawa, M. Amagai, M. Tanaka, T. Nishikawa

研究成果: Article

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Eosinophilic pustular folliculitis (EPF) is characterized by erythematous patches of large follicular papules and pustules involving mainly the face. Although various treatments have been attempted for EPF, including systemic and topical steroid, diaphenylsulphone, colchicine, minocycline as well as UVB phototherapy, there is no consensus on the first choice of treatment. We report a typical case and summarize 25 patients with EPF treated in our hospital between 1978 and 1998. Indomethacin was most frequently used (12/25) and showed clinical improvement in the majority of the cases (11/12). The effect of indomethacin was usually observed within 1-2 weeks after initiation of treatment. Decrease of peripheral blood eosinophils accompanied the clinical improvement. Thus, indomethacin should be considered as a first choice of treatment for EPF.

元の言語English
ページ(範囲)179-181
ページ数3
ジャーナルClinical and Experimental Dermatology
26
発行部数2
DOI
出版物ステータスPublished - 2001 4 18

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ASJC Scopus subject areas

  • Dermatology

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