Epstein-Barr virus-associated T/natural killer-cell lymphomas in the elderly: The first consensus meeting in Kofu 2013

Toshihisa Hamada, Shigeo Nakamura, Young Hyeh Ko, Tadashi Yoshino, Koichi Ohshima, Takamitsu Matsuzawa, Keiko Miura, Toshifumi Takahashi, Hisashi Nomura, Tomomi Hoshino, Daisuke Suzuki, Shinji Shimada, Keiji Iwatsuki

研究成果: Article査読

3 被引用数 (Scopus)

抄録

From a clinicopathological conference on nine elderly patients with Epstein-Barr virus (EBV)-associated T/natural killer (NK)-cell lymphoma, we have addressed the patients' backgrounds, clinical manifestations, histopathological findings, cytogenesis, complications and prognoses. Among these elderly patients (>65 years old), seven patients had extranodal NK/T-cell lymphoma, nasal type (ENKL) with an NK-cell phenotype, and two patients had EBV + T-cell lymphomas or lymphoproliferative disorders (LPD) with cutaneous lesions mimicking pityriasis lichenoides et varioliformis acuta (PLEVA) or hydroa vacciniforme (HV). No patients had a previous episode of EBV-related symptoms such as infectious mononucleosis, chronic active EBV infection, HV or hypersensitivity to mosquito bites. Elderly patients with ENKL may show the centroblastoid variant. EBV+CD8+CD56 +/- lymphocytes may be responsible for the development of PLEVA or HV-like cutaneous lesions in the elderly.

本文言語English
ページ(範囲)40-42
ページ数3
ジャーナルJournal of Dermatology
41
1
DOI
出版ステータスPublished - 2014 1月
外部発表はい

ASJC Scopus subject areas

  • 皮膚病学

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