Estrogens maintain bone mass by regulating expression of genes controlling function and life span in mature osteoclasts

Medicine & Life Sciences

• Osteoclasts 81%
• Longevity 70%
• Estrogens 64%
• Gene Expression 47%
• Bone and Bones 46%
• Estrogen Receptor alpha 41%
• Bone Resorption 14%
• Osteoblasts 13%
• Gene Knockout Techniques 8%
• Fas Ligand Protein 8%
• Cytoplasmic and Nuclear Receptors 7%
• Bone Marrow Cells 6%
• Knockout Mice 6%
• Testosterone 6%
• Genes 5%
• Phenotype 4%
• In Vitro Techniques 3%

Arts & Humanities

• Estrogen 100%
• Life Span 90%
• Gene 69%
• Mouse 16%
• Cells 12%
• Fatty Acids 8%
• Bone Marrow 8%
• Testosterone 8%
• Direct Action 7%
• Phenotype 6%
• Progression 6%
• Vitality 6%
• Manipulation 5%
• Nucleus 5%

Chemical Compounds

• Estrogen 84%
• Testosterone 7%
• Ablation 7%
• Reduction 2%
• Ligand 2%