Evaluating home blood pressure in treated hypertensives in comparison with the referential value of casual screening of blood pressure: The Ohasama study

Daisaku Yasui, Kei Asayama, Noriko Takada, Takayoshi Ohkubo, Masahiro Kikuya, Azusa Hara, Takuo Hirose, Taku Obara, Hirohito Metoki, Ryusuke Inoue, Kazuhito Totsune, Haruhisa Hoshi, Hiroshi Satoh, Jan A. Staessen, Yutaka Imai

研究成果: Article

6 引用 (Scopus)

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OBJECTIVE: The target home blood pressure (BP) levels for antihypertensive treatment have not been fully investigated. We estimated home BP values that corresponded to the referential values of casual screening of BP using reduced major axis (RMA) regression for data from untreated and treated individuals in a general population. METHODS: The study included 2651 participants (778 treated) aged 20 years or above. The relationships between casual BP and home BP were examined using RMA regression to consider measurement errors. We calculated estimated home BP values that corresponded to casual BP using the regression equations. RESULTS: Although casual BPs and home BPs were significantly correlated (all: P<0.0001), the coefficients of determination in multiple regression were higher in untreated individuals than those in treated ones. When RMA regression was applied between casual BP (x) and morning home BP (y), the equations were expressed as y=0.78x+26.55 (systolic BP) and y=0.84x+14.34 (diastolic BP) in treated individuals and y=0.79x+19.29 (systolic BP) and y=0.85x+9.94 (diastolic BP) in untreated ones. The estimated home BPs corresponded to 140/90 mmHg of casual BP: 135.8/89.8 mmHg (morning), 132.2/86.6 mmHg (evening), and 133.9/87.8 mmHg (average) in treated individuals and 129.2/86.7 mmHg (morning), 127.8/84.8 mmHg (evening), and 128.2/85.2 mmHg (average) in untreated individuals. CONCLUSION: We estimated the referential values of home BP in treated hypertensives using a regression model; however, further intervention studies on home BP are needed to clarify the target treatment goals of home BP.

元の言語English
ページ(範囲)89-95
ページ数7
ジャーナルBlood Pressure Monitoring
17
発行部数3
DOI
出版物ステータスPublished - 2012 6 1
外部発表Yes

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Blood Pressure
Antihypertensive Agents

ASJC Scopus subject areas

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine
  • Assessment and Diagnosis
  • Advanced and Specialised Nursing

これを引用

Evaluating home blood pressure in treated hypertensives in comparison with the referential value of casual screening of blood pressure : The Ohasama study. / Yasui, Daisaku; Asayama, Kei; Takada, Noriko; Ohkubo, Takayoshi; Kikuya, Masahiro; Hara, Azusa; Hirose, Takuo; Obara, Taku; Metoki, Hirohito; Inoue, Ryusuke; Totsune, Kazuhito; Hoshi, Haruhisa; Satoh, Hiroshi; Staessen, Jan A.; Imai, Yutaka.

:: Blood Pressure Monitoring, 巻 17, 番号 3, 01.06.2012, p. 89-95.

研究成果: Article

Yasui, D, Asayama, K, Takada, N, Ohkubo, T, Kikuya, M, Hara, A, Hirose, T, Obara, T, Metoki, H, Inoue, R, Totsune, K, Hoshi, H, Satoh, H, Staessen, JA & Imai, Y 2012, 'Evaluating home blood pressure in treated hypertensives in comparison with the referential value of casual screening of blood pressure: The Ohasama study', Blood Pressure Monitoring, 巻. 17, 番号 3, pp. 89-95. https://doi.org/10.1097/MBP.0b013e328351de34
Yasui, Daisaku ; Asayama, Kei ; Takada, Noriko ; Ohkubo, Takayoshi ; Kikuya, Masahiro ; Hara, Azusa ; Hirose, Takuo ; Obara, Taku ; Metoki, Hirohito ; Inoue, Ryusuke ; Totsune, Kazuhito ; Hoshi, Haruhisa ; Satoh, Hiroshi ; Staessen, Jan A. ; Imai, Yutaka. / Evaluating home blood pressure in treated hypertensives in comparison with the referential value of casual screening of blood pressure : The Ohasama study. :: Blood Pressure Monitoring. 2012 ; 巻 17, 番号 3. pp. 89-95.
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abstract = "OBJECTIVE: The target home blood pressure (BP) levels for antihypertensive treatment have not been fully investigated. We estimated home BP values that corresponded to the referential values of casual screening of BP using reduced major axis (RMA) regression for data from untreated and treated individuals in a general population. METHODS: The study included 2651 participants (778 treated) aged 20 years or above. The relationships between casual BP and home BP were examined using RMA regression to consider measurement errors. We calculated estimated home BP values that corresponded to casual BP using the regression equations. RESULTS: Although casual BPs and home BPs were significantly correlated (all: P<0.0001), the coefficients of determination in multiple regression were higher in untreated individuals than those in treated ones. When RMA regression was applied between casual BP (x) and morning home BP (y), the equations were expressed as y=0.78x+26.55 (systolic BP) and y=0.84x+14.34 (diastolic BP) in treated individuals and y=0.79x+19.29 (systolic BP) and y=0.85x+9.94 (diastolic BP) in untreated ones. The estimated home BPs corresponded to 140/90 mmHg of casual BP: 135.8/89.8 mmHg (morning), 132.2/86.6 mmHg (evening), and 133.9/87.8 mmHg (average) in treated individuals and 129.2/86.7 mmHg (morning), 127.8/84.8 mmHg (evening), and 128.2/85.2 mmHg (average) in untreated individuals. CONCLUSION: We estimated the referential values of home BP in treated hypertensives using a regression model; however, further intervention studies on home BP are needed to clarify the target treatment goals of home BP.",
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author = "Daisaku Yasui and Kei Asayama and Noriko Takada and Takayoshi Ohkubo and Masahiro Kikuya and Azusa Hara and Takuo Hirose and Taku Obara and Hirohito Metoki and Ryusuke Inoue and Kazuhito Totsune and Haruhisa Hoshi and Hiroshi Satoh and Staessen, {Jan A.} and Yutaka Imai",
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T1 - Evaluating home blood pressure in treated hypertensives in comparison with the referential value of casual screening of blood pressure

T2 - The Ohasama study

AU - Yasui, Daisaku

AU - Asayama, Kei

AU - Takada, Noriko

AU - Ohkubo, Takayoshi

AU - Kikuya, Masahiro

AU - Hara, Azusa

AU - Hirose, Takuo

AU - Obara, Taku

AU - Metoki, Hirohito

AU - Inoue, Ryusuke

AU - Totsune, Kazuhito

AU - Hoshi, Haruhisa

AU - Satoh, Hiroshi

AU - Staessen, Jan A.

AU - Imai, Yutaka

PY - 2012/6/1

Y1 - 2012/6/1

N2 - OBJECTIVE: The target home blood pressure (BP) levels for antihypertensive treatment have not been fully investigated. We estimated home BP values that corresponded to the referential values of casual screening of BP using reduced major axis (RMA) regression for data from untreated and treated individuals in a general population. METHODS: The study included 2651 participants (778 treated) aged 20 years or above. The relationships between casual BP and home BP were examined using RMA regression to consider measurement errors. We calculated estimated home BP values that corresponded to casual BP using the regression equations. RESULTS: Although casual BPs and home BPs were significantly correlated (all: P<0.0001), the coefficients of determination in multiple regression were higher in untreated individuals than those in treated ones. When RMA regression was applied between casual BP (x) and morning home BP (y), the equations were expressed as y=0.78x+26.55 (systolic BP) and y=0.84x+14.34 (diastolic BP) in treated individuals and y=0.79x+19.29 (systolic BP) and y=0.85x+9.94 (diastolic BP) in untreated ones. The estimated home BPs corresponded to 140/90 mmHg of casual BP: 135.8/89.8 mmHg (morning), 132.2/86.6 mmHg (evening), and 133.9/87.8 mmHg (average) in treated individuals and 129.2/86.7 mmHg (morning), 127.8/84.8 mmHg (evening), and 128.2/85.2 mmHg (average) in untreated individuals. CONCLUSION: We estimated the referential values of home BP in treated hypertensives using a regression model; however, further intervention studies on home BP are needed to clarify the target treatment goals of home BP.

AB - OBJECTIVE: The target home blood pressure (BP) levels for antihypertensive treatment have not been fully investigated. We estimated home BP values that corresponded to the referential values of casual screening of BP using reduced major axis (RMA) regression for data from untreated and treated individuals in a general population. METHODS: The study included 2651 participants (778 treated) aged 20 years or above. The relationships between casual BP and home BP were examined using RMA regression to consider measurement errors. We calculated estimated home BP values that corresponded to casual BP using the regression equations. RESULTS: Although casual BPs and home BPs were significantly correlated (all: P<0.0001), the coefficients of determination in multiple regression were higher in untreated individuals than those in treated ones. When RMA regression was applied between casual BP (x) and morning home BP (y), the equations were expressed as y=0.78x+26.55 (systolic BP) and y=0.84x+14.34 (diastolic BP) in treated individuals and y=0.79x+19.29 (systolic BP) and y=0.85x+9.94 (diastolic BP) in untreated ones. The estimated home BPs corresponded to 140/90 mmHg of casual BP: 135.8/89.8 mmHg (morning), 132.2/86.6 mmHg (evening), and 133.9/87.8 mmHg (average) in treated individuals and 129.2/86.7 mmHg (morning), 127.8/84.8 mmHg (evening), and 128.2/85.2 mmHg (average) in untreated individuals. CONCLUSION: We estimated the referential values of home BP in treated hypertensives using a regression model; however, further intervention studies on home BP are needed to clarify the target treatment goals of home BP.

KW - antihypertensive drugs

KW - corresponding criteria

KW - general population

KW - home blood pressure monitoring

KW - reduced major axis regression

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