Evaluation of biofouling in stainless microfluidic channels for implantable multilayered dialysis device

Takashi Ota, Naoya To, Yoshihiko Kanno, Norihisa Miki

研究成果: Article査読

4 被引用数 (Scopus)

抄録

An implantable artificial kidney can markedly improve the quality of life of renal disease patients. Our group has developed an implantable multilayered dialysis system consisting of microfluidic channels and dialysis membranes. Long-term evaluation is necessary for implant devices where biofouling is a critical factor, culminating in the deterioration of dialysis performance. Our previous work revealed that surface conditions, which depend on the manufacturing process, determine the amount of biofouling, and that electrolytic etching is the most suitable technique for forming a channel wall free of biofouling. In this study, we investigated the electrolytic etching conditions in detail. We conducted in vitro experiments for 7 d and evaluated the adhesion of biomaterials by scanning electron microscopy. The experiments revealed that a surface mirrorfinished by electrolytic etching effectively prevents biofouling.

本文言語English
論文番号06GN10
ジャーナルJapanese journal of applied physics
56
6
DOI
出版ステータスPublished - 2017 6

ASJC Scopus subject areas

  • 工学(全般)
  • 物理学および天文学(全般)

フィンガープリント

「Evaluation of biofouling in stainless microfluidic channels for implantable multilayered dialysis device」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル