TY - JOUR
T1 - Evaluation of Gleason Grade Group 5 in a Contemporary Prostate Cancer Grading System and Literature Review
AU - Kamitani, Rei
AU - Matsumoto, Kazuhiro
AU - Kosaka, Takeo
AU - Takeda, Toshikazu
AU - Hashiguchi, Akinori
AU - Tanaka, Nobuyuki
AU - Morita, Shinya
AU - Mizuno, Ryuichi
AU - Shinojima, Toshiaki
AU - Asanuma, Hiroshi
AU - Oya, Mototsugu
N1 - Publisher Copyright:
© 2020 Elsevier Inc.
PY - 2021/2
Y1 - 2021/2
N2 - The aim of this study was to validate the contemporary grading system. Our follow-up study revealed that men with Gleason score (GS) 4+5 and those with Gleason grade group 4 had a similar prognosis. However, there was a significant discrepancy in prognosis between GS 4+5 and GS 5+4 or higher. Gleason grade groups 4 and 5 in the contemporary grading system should be reviewed.
AB - The aim of this study was to validate the contemporary grading system. Our follow-up study revealed that men with Gleason score (GS) 4+5 and those with Gleason grade group 4 had a similar prognosis. However, there was a significant discrepancy in prognosis between GS 4+5 and GS 5+4 or higher. Gleason grade groups 4 and 5 in the contemporary grading system should be reviewed.
KW - Biochemical recurrence
KW - Castration-resistant prostate cancer
KW - Gleason score
KW - Grade group
KW - High-risk prostate cancer
UR - http://www.scopus.com/inward/record.url?scp=85089888666&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85089888666&partnerID=8YFLogxK
U2 - 10.1016/j.clgc.2020.08.001
DO - 10.1016/j.clgc.2020.08.001
M3 - Article
C2 - 32863190
AN - SCOPUS:85089888666
SN - 1558-7673
VL - 19
SP - 69-75.e5
JO - Clinical Genitourinary Cancer
JF - Clinical Genitourinary Cancer
IS - 1
ER -
