Evaluation of the binding force between a biotinylated microbubble and a streptavidin-coated surface by ultrasound radiation

Toshihiko Sugiura, Klazina Kooiman, Marcia Emmer, Hendrik J. Vos, Annemieke Van Wamel, Nico De Jong

研究成果: Conference contribution

抜粋

For molecular imaging using ultrasound, targeted ultrasound contrast agents are used that consist of encapsulated gas microbubbles. For this application, the strength of adhesion between a microbubble and a cell surface is an important factor. This research focuses on the evaluation of the binding force between a streptavidin-coated surface, which mimics a cell surface, and biotinylated lipid coated microbubbles by detaching the microbubbles with ultrasound radiation force. Our results show that ultrasound radiation force can be used to determine the binding force between a targeted microbubble and a surface.

元の言語English
ホスト出版物のタイトル2009 IEEE International Ultrasonics Symposium and Short Courses, IUS 2009
DOI
出版物ステータスPublished - 2009 12 1
イベント2009 IEEE International Ultrasonics Symposium, IUS 2009 - Rome, Italy
継続期間: 2009 9 202009 9 23

出版物シリーズ

名前Proceedings - IEEE Ultrasonics Symposium
ISSN(印刷物)1051-0117

Other

Other2009 IEEE International Ultrasonics Symposium, IUS 2009
Italy
Rome
期間09/9/2009/9/23

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

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  • これを引用

    Sugiura, T., Kooiman, K., Emmer, M., Vos, H. J., Van Wamel, A., & De Jong, N. (2009). Evaluation of the binding force between a biotinylated microbubble and a streptavidin-coated surface by ultrasound radiation. : 2009 IEEE International Ultrasonics Symposium and Short Courses, IUS 2009 [5441969] (Proceedings - IEEE Ultrasonics Symposium). https://doi.org/10.1109/ULTSYM.2009.5441969