Ex vivo and in vivo evaluation of the blood compatibility of surface- modified polyurethane catheters

Hiroyuki Inoue, Keiji Fujimoto, Yoshikimi Uyama, Yoshito Ikada

研究成果: Article査読

27 被引用数 (Scopus)

抄録

An assessment method relevant to the expected clinical application of biomaterials, when they are studied for improvement of blood-surface compatibility, is established. Segmented polyetherurethane (PU) was selected for the study as a polymer substrate for surface modification. The PU modification was carried out by surface graft polymerization of the water-soluble monomers acrylamide (AAm) and dimethyl acrylamide (DMAA). The in vivo blood compatibility of polyurethane was evaluated by implanting the catheter tube in the inferior vena cava of rabbits from the femoral vein after ligation of a distal site of the exposed femoral vein.

本文言語English
ページ(範囲)255-264
ページ数10
ジャーナルJournal of Biomedical Materials Research
35
2
DOI
出版ステータスPublished - 1997 5
外部発表はい

ASJC Scopus subject areas

  • 生体材料
  • 生体医工学

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