抄録
Molecular genetic study of Caenorhabditis elegans revealed the cell death-executing gene ced-3. Structural and functional similarities between CED-3 and mammalian ICE family (caspase) gene products provide the evidence that mammalian caspases are common mediators in executing programmed cell death. These findings suggest that the execution mechanisms of cell death by caspase family protease may be evolutionarily conserved from worms to mammals. This report summarizes the unique properties of caspases in apoptosis.
| 本文言語 | English |
|---|---|
| ページ（範囲） | 66-70 |
| ページ数 | 5 |
| ジャーナル | Heart and vessels |
| 巻 | 12 |
| 号 | SUPPL. 12 |
| 出版ステータス | Published - 1997 12月 1 |
| 外部発表 | はい |
ASJC Scopus subject areas
- 循環器および心血管医学