Expression patterns of musashi homologs of the ascidians, Halocynthia roretzi and Ciona intestinalis

Takeshi Kawashima, Akikazu R. Murakami, Michio Ogasawara, Kimio J. Tanaka, Ryuji Isoda, Yasunori Sasakura, Takahito Nishikata, Hideyuki Okano, Kazuhiro W. Makabe

研究成果: Article査読

26 被引用数 (Scopus)

抄録

The gene family encoding RNA-binding proteins includes important regulators involved in the neurogenesis in both protostomes and deuterostomes. We isolated cDNAs of the ascidian homolog of one of the RNA-binding proteins, MUSASHI, from Halocynthia roretzi and Ciona intestinalis. The predicted amino acid sequences contained two RNA-recognition and RNA-binding motifs in the N-terminus and an ascidian-specific YG-rich domain in the C-terminus. Maternal transcripts of musashi were ubiquitous in early cleavage-stage embryos. Ascidian musashi had three domains of zygotic expression: the brain, nerve cord, and mesenchyma. The temporal order of the onset in these domains was highly divergent between the two species of ascidian examined.

本文言語English
ページ(範囲)162-165
ページ数4
ジャーナルDevelopment Genes and Evolution
210
3
DOI
出版ステータスPublished - 2000
外部発表はい

ASJC Scopus subject areas

  • 遺伝学
  • 発生生物学

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