We studied the diffusely increased fluorodeoxyglucose (FDG) uptake on positron emission tomography (PET) in the vertebrae of a 74-year-old man with granulocyte colony stimulating factor (G-CSF) producing pulmonary pleomorphic carcinoma. The PET findings were due to bone marrow hyperplasia induced by G-CSF and indicate that we should be careful in differentiating these findings from bone metastases and complications with hematological disease. The Tc-99m HMDP bone scan was normal. PET image in another patient with lung cancer after treatment by rhG-CSF resembles that of the described case. PET imaging in a patient with G-CSF producing carcinoma is probably rare.
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging