Fabrication of transplantable 3D-neuronal network

Midori Kato-Negishi, Yukiko Tsuda, Hiroaki Onoe, Shoji Takeuchi

研究成果: Conference contribution

抄録

This paper describes a method to fabricate a transplantable three-dimensional (3D) neuronal network using the neu-rospheroid network (NSN) on a polydimethylsiloxane (PDMS) microchamber array. We developed a technique, termed the "NSN-stamping method", to transfer the NSN onto other substrates without any chemical treatment. Using this method, we demonstrate that different NSNs were stacked and formed 3D neuronal tissue, and then 3D-NSN could be transferred onto the cortical tissue at a high transfer rate. This method would be an extremely effective tool for tissue buildup in neuronal tissue engineering and provides a simple approach to the transplantation of 3D neuronal network.

元の言語English
ホスト出版物のタイトル14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
ページ632-634
ページ数3
1
出版物ステータスPublished - 2010
外部発表Yes
イベント14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010 - Groningen, Netherlands
継続期間: 2010 10 32010 10 7

Other

Other14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
Netherlands
Groningen
期間10/10/310/10/7

Fingerprint

Tissue
Fabrication
Stamping
Polydimethylsiloxane
Tissue engineering
Substrates

ASJC Scopus subject areas

  • Control and Systems Engineering

これを引用

Kato-Negishi, M., Tsuda, Y., Onoe, H., & Takeuchi, S. (2010). Fabrication of transplantable 3D-neuronal network. : 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010 (巻 1, pp. 632-634)

Fabrication of transplantable 3D-neuronal network. / Kato-Negishi, Midori; Tsuda, Yukiko; Onoe, Hiroaki; Takeuchi, Shoji.

14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010. 巻 1 2010. p. 632-634.

研究成果: Conference contribution

Kato-Negishi, M, Tsuda, Y, Onoe, H & Takeuchi, S 2010, Fabrication of transplantable 3D-neuronal network. : 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010. 巻. 1, pp. 632-634, 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010, Groningen, Netherlands, 10/10/3.
Kato-Negishi M, Tsuda Y, Onoe H, Takeuchi S. Fabrication of transplantable 3D-neuronal network. : 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010. 巻 1. 2010. p. 632-634
Kato-Negishi, Midori ; Tsuda, Yukiko ; Onoe, Hiroaki ; Takeuchi, Shoji. / Fabrication of transplantable 3D-neuronal network. 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010. 巻 1 2010. pp. 632-634
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