Aim: To identify the association between possible factors and depression among post-percutaneous coronary intervention patients with acute coronary syndrome. Design: Prospective cohort study. Methods: Sixty-eight post-percutaneous coronary intervention patients with acute coronary syndrome were enrolled between January 2016 - June 2017. The Hospital Anxiety and Depression Scale scores at 1–3 months after discharge were regressed onto uncertainty in illness and other clinical factors based on the Roy Adaptation Model. Results: Thirty-six patients were included in the final analysis. Higher baseline depression scores, higher changes in uncertainty in illness and feeling annoyed by troublesome tasks after discharge were associated with higher depressive scores at 1 month after discharge. Careful observation and support of patients’ ineffective responses in self-concept mode may be effective in preventing depression.
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