Feasibility Study of a Newly Developed Hybrid Energy Device Used During Laparoscopic Liver Resection in a Porcine Model

Taiga Wakabayashi, Yuta Abe, Akishige Kanazawa, Go Oshima, Shintaro Kodai, Kazuhisa Ehara, Yusuke Kinugasa, Takahiro Kinoshita, Akinari Nomura, Hirofumi Kawakubo, Yuukou Kitagawa

研究成果: Article

抄録

Background. Although various devices have been clinically used for laparoscopic liver resection (LLR), the best device for liver parenchymal transection remains unknown. Olympus Corp (Tokyo, Japan) developed a laparoscopic hybrid pencil (LHP) device, which is the first electric knife to combine ultrasound and electric energy with a monopolar output. We aimed to evaluate the feasibility of using the LHP device and to compare it with the laparoscopic monopolar pencil (LMP) and laparoscopic ultrasonic shears (LUS) devices for LLR in a porcine model. Methods. Nine male piglets underwent laparoscopic liver lobe transections using each device. The operative parameters were evaluated in the 3 groups (n = 24 lobes) during the acute study period. The imaging findings from contrast-enhanced computed tomography and histopathological findings of autopsy on postoperative day 7 were compared among groups (n = 6 piglets) during the long-term study. Results. The transection time was shorter (P =.001); there was less blood loss (P =.018); and tip cleaning (P <.001) and instrument changes were less often required (P <.001) in the LHP group than in the LMP group. The LHP group had fewer instances of bleeding (P <.001) and coagulator usage (P <.001) than did the LUS group. In the long-term study, no postoperative adverse events occurred in the 3 groups. The thermal spread and depth of the LHP device were equivalent to those of the LMP and LUS devices (vs LMP: P =.226 and.159; vs LUS: P = 1.000 and.574). Conclusions. The LHP device may be an efficient device for LLR if it can be applied to human surgery.

元の言語English
ジャーナルSurgical Innovation
DOI
出版物ステータスAccepted/In press - 2018 1 1

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Feasibility Studies
Swine
Equipment and Supplies
Liver
Ultrasonics
Tokyo
Autopsy
Japan
Hot Temperature
Tomography
Hemorrhage

ASJC Scopus subject areas

  • Surgery

これを引用

Feasibility Study of a Newly Developed Hybrid Energy Device Used During Laparoscopic Liver Resection in a Porcine Model. / Wakabayashi, Taiga; Abe, Yuta; Kanazawa, Akishige; Oshima, Go; Kodai, Shintaro; Ehara, Kazuhisa; Kinugasa, Yusuke; Kinoshita, Takahiro; Nomura, Akinari; Kawakubo, Hirofumi; Kitagawa, Yuukou.

:: Surgical Innovation, 01.01.2018.

研究成果: Article

Wakabayashi, Taiga ; Abe, Yuta ; Kanazawa, Akishige ; Oshima, Go ; Kodai, Shintaro ; Ehara, Kazuhisa ; Kinugasa, Yusuke ; Kinoshita, Takahiro ; Nomura, Akinari ; Kawakubo, Hirofumi ; Kitagawa, Yuukou. / Feasibility Study of a Newly Developed Hybrid Energy Device Used During Laparoscopic Liver Resection in a Porcine Model. :: Surgical Innovation. 2018.
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title = "Feasibility Study of a Newly Developed Hybrid Energy Device Used During Laparoscopic Liver Resection in a Porcine Model",
abstract = "Background. Although various devices have been clinically used for laparoscopic liver resection (LLR), the best device for liver parenchymal transection remains unknown. Olympus Corp (Tokyo, Japan) developed a laparoscopic hybrid pencil (LHP) device, which is the first electric knife to combine ultrasound and electric energy with a monopolar output. We aimed to evaluate the feasibility of using the LHP device and to compare it with the laparoscopic monopolar pencil (LMP) and laparoscopic ultrasonic shears (LUS) devices for LLR in a porcine model. Methods. Nine male piglets underwent laparoscopic liver lobe transections using each device. The operative parameters were evaluated in the 3 groups (n = 24 lobes) during the acute study period. The imaging findings from contrast-enhanced computed tomography and histopathological findings of autopsy on postoperative day 7 were compared among groups (n = 6 piglets) during the long-term study. Results. The transection time was shorter (P =.001); there was less blood loss (P =.018); and tip cleaning (P <.001) and instrument changes were less often required (P <.001) in the LHP group than in the LMP group. The LHP group had fewer instances of bleeding (P <.001) and coagulator usage (P <.001) than did the LUS group. In the long-term study, no postoperative adverse events occurred in the 3 groups. The thermal spread and depth of the LHP device were equivalent to those of the LMP and LUS devices (vs LMP: P =.226 and.159; vs LUS: P = 1.000 and.574). Conclusions. The LHP device may be an efficient device for LLR if it can be applied to human surgery.",
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author = "Taiga Wakabayashi and Yuta Abe and Akishige Kanazawa and Go Oshima and Shintaro Kodai and Kazuhisa Ehara and Yusuke Kinugasa and Takahiro Kinoshita and Akinari Nomura and Hirofumi Kawakubo and Yuukou Kitagawa",
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T1 - Feasibility Study of a Newly Developed Hybrid Energy Device Used During Laparoscopic Liver Resection in a Porcine Model

AU - Wakabayashi, Taiga

AU - Abe, Yuta

AU - Kanazawa, Akishige

AU - Oshima, Go

AU - Kodai, Shintaro

AU - Ehara, Kazuhisa

AU - Kinugasa, Yusuke

AU - Kinoshita, Takahiro

AU - Nomura, Akinari

AU - Kawakubo, Hirofumi

AU - Kitagawa, Yuukou

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Background. Although various devices have been clinically used for laparoscopic liver resection (LLR), the best device for liver parenchymal transection remains unknown. Olympus Corp (Tokyo, Japan) developed a laparoscopic hybrid pencil (LHP) device, which is the first electric knife to combine ultrasound and electric energy with a monopolar output. We aimed to evaluate the feasibility of using the LHP device and to compare it with the laparoscopic monopolar pencil (LMP) and laparoscopic ultrasonic shears (LUS) devices for LLR in a porcine model. Methods. Nine male piglets underwent laparoscopic liver lobe transections using each device. The operative parameters were evaluated in the 3 groups (n = 24 lobes) during the acute study period. The imaging findings from contrast-enhanced computed tomography and histopathological findings of autopsy on postoperative day 7 were compared among groups (n = 6 piglets) during the long-term study. Results. The transection time was shorter (P =.001); there was less blood loss (P =.018); and tip cleaning (P <.001) and instrument changes were less often required (P <.001) in the LHP group than in the LMP group. The LHP group had fewer instances of bleeding (P <.001) and coagulator usage (P <.001) than did the LUS group. In the long-term study, no postoperative adverse events occurred in the 3 groups. The thermal spread and depth of the LHP device were equivalent to those of the LMP and LUS devices (vs LMP: P =.226 and.159; vs LUS: P = 1.000 and.574). Conclusions. The LHP device may be an efficient device for LLR if it can be applied to human surgery.

AB - Background. Although various devices have been clinically used for laparoscopic liver resection (LLR), the best device for liver parenchymal transection remains unknown. Olympus Corp (Tokyo, Japan) developed a laparoscopic hybrid pencil (LHP) device, which is the first electric knife to combine ultrasound and electric energy with a monopolar output. We aimed to evaluate the feasibility of using the LHP device and to compare it with the laparoscopic monopolar pencil (LMP) and laparoscopic ultrasonic shears (LUS) devices for LLR in a porcine model. Methods. Nine male piglets underwent laparoscopic liver lobe transections using each device. The operative parameters were evaluated in the 3 groups (n = 24 lobes) during the acute study period. The imaging findings from contrast-enhanced computed tomography and histopathological findings of autopsy on postoperative day 7 were compared among groups (n = 6 piglets) during the long-term study. Results. The transection time was shorter (P =.001); there was less blood loss (P =.018); and tip cleaning (P <.001) and instrument changes were less often required (P <.001) in the LHP group than in the LMP group. The LHP group had fewer instances of bleeding (P <.001) and coagulator usage (P <.001) than did the LUS group. In the long-term study, no postoperative adverse events occurred in the 3 groups. The thermal spread and depth of the LHP device were equivalent to those of the LMP and LUS devices (vs LMP: P =.226 and.159; vs LUS: P = 1.000 and.574). Conclusions. The LHP device may be an efficient device for LLR if it can be applied to human surgery.

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KW - hepatobiliary

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