Feasibility Study of Partial Submucosal Injection Technique Combining Underwater EMR for Superficial Duodenal Epithelial Tumors

Yusaku Takatori, Motohiko Kato, Teppei Masunaga, Yoko Kubosawa, Mari Mizutani, Yoshiyuki Kiguchi, Noriko Matsuura, Atsushi Nakayama, Tadateru Maehata, Naohisa Yahagi

研究成果: Article査読

1 被引用数 (Scopus)

抄録

Background and Aims: Endoscopic mucosal resection (EMR) and Underwater EMR have been reported as effective endoscopic treatment for superficial duodenal tumor (SDET). However, a notable problem of EMR for SDET is technical difficulty for the lesion with non-lifting sign, and it of UEMR is that en bloc resection rate is relatively low. Therefore, we performed partial submucosal injection combining UEMR (PI-UEMR). The aim of this study is to evaluate feasibility and safety of this technique for duodenal tumor. Methods: This is a prospective observational study from tertiary care hospital. We performed PI-UEMR in patients with SDET that is 13–20 mm in diameter, or less than 13 mm with technical difficulty for EMR and UEMR from January 2019 to March 2020. Primary outcome was en bloc resection rate. Secondary outcomes were R0 resection rate, mean total procedure time, intra- and post-procedure complication. Results: Thirty patients were included in this study. Mean age was 62 ± 12 years old. Three fourths lesions were located at anal side from major papilla. Median lesion size was 12 mm [IQR 10–16 mm]. Twenty-four cases were taken endoscopic biopsy in prior hospital and observed biopsy scar. En bloc resection rate was 97%. Ro resection rate was 83%. Mean total procedure time was 17 ± 12 min. And there was an only one case of complication, intra-procedure bleeding that was controllable endoscopically. Conclusions: PI-UEMR might be very useful and safe technique of endoscopic resection for SDET including relatively large lesions.

本文言語English
ジャーナルDigestive Diseases and Sciences
DOI
出版ステータスAccepted/In press - 2021

ASJC Scopus subject areas

  • 生理学
  • 消化器病学

フィンガープリント

「Feasibility Study of Partial Submucosal Injection Technique Combining Underwater EMR for Superficial Duodenal Epithelial Tumors」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル