Fiber-optic conical microsensors for surface plasmon resonance using chemically etched single-mode fiber

Kazuyoshi Kurihara, Hiroyuki Ohkawa, Yuzuru Iwasaki, Osamu Niwa, Tatsuya Tobita, Koji Suzuki

研究成果: Article査読

81 被引用数 (Scopus)

抄録

A new type of the fiber-optic microsensor for surface plasmon resonance (SPR) was created on the basis of the fabrication technology of optical fiber probes in near-field scanning optical microscopy (NSOM). The newly developed SPR microsensors were prepared by coating a gold-metallic film on the chemically etched single-mode fiber containing a conical core. They were applied to the real-time monitoring of the refractive index (RI) of transparent liquids flowing in the microfluidic device. When SPR microsensors were chemically modified with a self-assembled monolayer presenting a hydroxyl group, they successfully responded to the refractive index from 1.33 to 1.40 RI with a sensitivity of 0.008 RI units that covers the interesting regions for SPR biosensor operated in a water solution.

本文言語English
ページ(範囲)165-170
ページ数6
ジャーナルAnalytica Chimica Acta
523
2
DOI
出版ステータスPublished - 2004 10 11

ASJC Scopus subject areas

  • 分析化学
  • 生化学
  • 環境化学
  • 分光学

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