Formal total synthesis of altohyrtin C (spongistatin 2). Part 2: Construction of fully elaborated ABCD and EF fragments

Takeshi Terauchi, Taisaku Tanaka, Taro Terauchi, Masataka Morita, Kyoko Kimijima, Ippei Sato, Wataru Shoji, Yasuhiro Nakamura, Tomoharu Tsukada, Takashi Tsunoda, Gouichirou Hayashi, Naoki Kanoh, Masaya Nakata

研究成果: Article査読

25 被引用数 (Scopus)

抄録

Coupling of the C1-C14 (AB) crotylstannane with the C15-C28 (CD) aldehyde followed by stereochemical arrangements gave the C1-C28 (ABCD) fragment of altohyrtin C. The C29-C44 (EF) fragment was also prepared. The syntheses of these two fragments, both of which were identical with those prepared by the Smith group, constitute a formal total synthesis of altohyrtin C.

本文言語English
ページ(範囲)7747-7751
ページ数5
ジャーナルTetrahedron Letters
44
42
DOI
出版ステータスPublished - 2003 10 13

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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