Function of DnaA protein, the initiator for chromosomal DNA replication in E. Coli

Tohru Mizushima

研究成果: Review article査読

抄録

DnaA protein is an initiator for chromosomal DNA replication in E. coli. We have examined the function of the protein to answer the following four questions; How DnaA protein is inactivated after DNA replication for the suppression of re-initiation? How DnaA protein is activated for the initiation of DNA replication? Does DnaA protein have functions other than that for DNA replication? Is DnaA protein is a good target for new antibiotics? In this review, I summarize our recent studies for these questions.

本文言語English
ページ(範囲)257-271
ページ数15
ジャーナルYakugaku Zasshi
118
7
DOI
出版ステータスPublished - 1998 7

ASJC Scopus subject areas

  • Pharmacology
  • Pharmaceutical Science

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