Galectin-3 as a regulator of the epithelial junction: Implications to wound repair and cancer

Pablo Argüeso, Jerome Mauris, Yuichi Uchino

研究成果: Article査読

14 被引用数 (Scopus)

抄録

Epithelial cells are closely connected to each other and to the extracellular matrix by a set of adhesive contacts that provide tissues with unique barrier properties and play a prominent role in cell morphology, tissue physiology, and cell signaling. This review highlights advances made in understanding the contributions of galectin-3, a carbohydrate-binding protein with affinity toward β-galactosides, as a modulator of epithelial junction assembly and function. The interactions of galectin-3 within adhesive structures are discussed in relation to wound healing and tumor progression.

本文言語English
ページ(範囲)1-6
ページ数6
ジャーナルTissue Barriers
3
3
DOI
出版ステータスPublished - 2015 7 3
外部発表はい

ASJC Scopus subject areas

  • 生化学
  • 組織学
  • 細胞生物学

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