Gatifloxacin resistance and mutations in gyrA after unsuccessful Helicobacter pylori eradication in Japan

Toshihiro Nishizawa, Hidekazu Suzuki, Kumiko Kurabayashi, Tatsuhiro Masaoka, Hiroe Muraoka, Mikiji Mori, Eisuke Iwasaki, Intetsu Kobayashi, Toshifumi Hibi

研究成果: Article査読

52 被引用数 (Scopus)

抄録

A high resistance rate (47.9%) to gatifloxacin (GAT; 8-methoxy fluoroquinolone) in Helicobacter pylori (H. pylori) strains from 48 Japanese patients is observed after unsuccessful H. pylori eradication. A significant association between MICs for GAT equal to or above 1 μg/ml and mutations of the gyrA gene of H. pylori was demonstrated.

本文言語English
ページ(範囲)1538-1540
ページ数3
ジャーナルAntimicrobial Agents and Chemotherapy
50
4
DOI
出版ステータスPublished - 2006 4

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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