A giant omphalocele was successfully treated with a two-step procedure. The first step was a three-staged operation with Gore-tex® sheet to elongate the abdominal muscular layer, and the second step was conservative treatment using the artificial dermis (Terudermis®) to attain effective epithelization at the residual skin defect areas. The proper combination therapy of surgical and conservative treatments may be effective for giant omphalocele because some novel materials and methods including silver-containing materials, povidone-iodine, artificial dermis and negative pressure wound therapy have become available. We report one optional treatment here. The best combination of these strategies for the treatment of giant omphalocele should be sought in the future.
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