Global protein-expression profiling for reclassification of malignant fibrous histiocytoma

Kazutaka Kikuta, Hideo Morioka, Akira Kawai, Tadashi Kondo

研究成果: Review article査読

1 被引用数 (Scopus)

抄録

According to the newest World Health Organization (WHO) classification for soft tissue tumors in 2013, malignant fibrous histiocytoma (MFH) has been gone. Most sarcomas called MFH were reclassified to be high-grade pleomorphic forms of leiomyosarcoma, liposarcoma, rhabdomyosarcoma, and other sarcomas by recent molecular technologies. However, about 10% to 15% of sarcomas called MFH before, still cannot be given a precise classification, and these are now called undifferentiated pleomorphic sarcoma or are still called MFH. Further molecular approaches including proteomic approaches are imperative to classify these unclassified sarcomas for improving clinical outcomes of the patients with soft tissue sarcomas. This article is part of a Special Issue entitled: Medical Proteomics.

本文言語English
ページ(範囲)696-701
ページ数6
ジャーナルBiochimica et Biophysica Acta - Proteins and Proteomics
1854
6
DOI
出版ステータスPublished - 2015 6 1

ASJC Scopus subject areas

  • 分析化学
  • 生物理学
  • 生化学
  • 分子生物学

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