Gradual progress of ACTH deficiency in a child with panhypopituitarism associated with pituitary stalk transection

Y. Hasegawa, Tomonobu Hasegawa, T. Yokoyama, S. Kotoh, Y. Tsuchiya

研究成果: Article

6 引用 (Scopus)

抄録

We present here a 13-year-old male with hypopituitarism which accompanied an insidious and gradual progress of ACTH deficiency. ACTH deficiency finally led to an overt crisis of adrenal insufficiency at the age of 12 years and 7 months. This patient is unique because the insidious and gradual progress has been proved by not only the laboratory results but also the clinical course for over 13 years. The cause of panhypopituitarism including ACTH deficiency is thought to have existed before or at the delivery because of the stalk transection seen on the magnetic resonance image (MRI). At the crisis, his laboratory results suggested that he had secondary adrenal insufficiency, whereas he showed normal adrenal function proved by the insulin tolerance test (ITT) at the age of 4 years. Abrupt crisis of secondary adrenal insufficiency developed at the age of 12 years, although he had been well until the crisis.

元の言語English
ページ(範囲)165-167
ページ数3
ジャーナルEndocrinologia Japonica
39
発行部数2
出版物ステータスPublished - 1992
外部発表Yes

Fingerprint

Adrenal Insufficiency
Pituitary Gland
Adrenocorticotropic Hormone
Hypopituitarism
Magnetic Resonance Spectroscopy
Insulin
Combined Pituitary Hormone Deficiency

ASJC Scopus subject areas

  • Endocrinology

これを引用

Gradual progress of ACTH deficiency in a child with panhypopituitarism associated with pituitary stalk transection. / Hasegawa, Y.; Hasegawa, Tomonobu; Yokoyama, T.; Kotoh, S.; Tsuchiya, Y.

:: Endocrinologia Japonica, 巻 39, 番号 2, 1992, p. 165-167.

研究成果: Article

@article{15a5d90ef5c24835af6cb6ac257aa551,
title = "Gradual progress of ACTH deficiency in a child with panhypopituitarism associated with pituitary stalk transection",
abstract = "We present here a 13-year-old male with hypopituitarism which accompanied an insidious and gradual progress of ACTH deficiency. ACTH deficiency finally led to an overt crisis of adrenal insufficiency at the age of 12 years and 7 months. This patient is unique because the insidious and gradual progress has been proved by not only the laboratory results but also the clinical course for over 13 years. The cause of panhypopituitarism including ACTH deficiency is thought to have existed before or at the delivery because of the stalk transection seen on the magnetic resonance image (MRI). At the crisis, his laboratory results suggested that he had secondary adrenal insufficiency, whereas he showed normal adrenal function proved by the insulin tolerance test (ITT) at the age of 4 years. Abrupt crisis of secondary adrenal insufficiency developed at the age of 12 years, although he had been well until the crisis.",
keywords = "gradual progress of ACTH deficiency, hypopituitarism, transection of pituitary stalk",
author = "Y. Hasegawa and Tomonobu Hasegawa and T. Yokoyama and S. Kotoh and Y. Tsuchiya",
year = "1992",
language = "English",
volume = "39",
pages = "165--167",
journal = "Endocrine Journal",
issn = "0918-8959",
publisher = "Japan Endocrine Society",
number = "2",

}

TY - JOUR

T1 - Gradual progress of ACTH deficiency in a child with panhypopituitarism associated with pituitary stalk transection

AU - Hasegawa, Y.

AU - Hasegawa, Tomonobu

AU - Yokoyama, T.

AU - Kotoh, S.

AU - Tsuchiya, Y.

PY - 1992

Y1 - 1992

N2 - We present here a 13-year-old male with hypopituitarism which accompanied an insidious and gradual progress of ACTH deficiency. ACTH deficiency finally led to an overt crisis of adrenal insufficiency at the age of 12 years and 7 months. This patient is unique because the insidious and gradual progress has been proved by not only the laboratory results but also the clinical course for over 13 years. The cause of panhypopituitarism including ACTH deficiency is thought to have existed before or at the delivery because of the stalk transection seen on the magnetic resonance image (MRI). At the crisis, his laboratory results suggested that he had secondary adrenal insufficiency, whereas he showed normal adrenal function proved by the insulin tolerance test (ITT) at the age of 4 years. Abrupt crisis of secondary adrenal insufficiency developed at the age of 12 years, although he had been well until the crisis.

AB - We present here a 13-year-old male with hypopituitarism which accompanied an insidious and gradual progress of ACTH deficiency. ACTH deficiency finally led to an overt crisis of adrenal insufficiency at the age of 12 years and 7 months. This patient is unique because the insidious and gradual progress has been proved by not only the laboratory results but also the clinical course for over 13 years. The cause of panhypopituitarism including ACTH deficiency is thought to have existed before or at the delivery because of the stalk transection seen on the magnetic resonance image (MRI). At the crisis, his laboratory results suggested that he had secondary adrenal insufficiency, whereas he showed normal adrenal function proved by the insulin tolerance test (ITT) at the age of 4 years. Abrupt crisis of secondary adrenal insufficiency developed at the age of 12 years, although he had been well until the crisis.

KW - gradual progress of ACTH deficiency

KW - hypopituitarism

KW - transection of pituitary stalk

UR - http://www.scopus.com/inward/record.url?scp=0026754545&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026754545&partnerID=8YFLogxK

M3 - Article

C2 - 1327727

AN - SCOPUS:0026754545

VL - 39

SP - 165

EP - 167

JO - Endocrine Journal

JF - Endocrine Journal

SN - 0918-8959

IS - 2

ER -