H1oo: A pre-embryonic H1 linker histone in search of a function

Mamoru Tanaka, Maki Kihara, Blazej Meczekalski, Gretchen J. King, Eli Y. Adashi

研究成果: Article査読

30 被引用数 (Scopus)

抄録

The mouse oocyte-specific linker histone H1oo (1) constitutes a novel mammalian homologue of the oocyte-specific linker histone B4 of the frog and of the cs-H1 linker histone of the sea urchin; (2) is expressed as early as the germinal vesicle (PI) stage oocyte, persisting into the MII stage oocyte, the oocytic polar bodies, and the 2-cell embryo, extinction becoming apparent at the 4-8 cell embryonic stage; and (3) may play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure.

本文言語English
ページ(範囲)5-9
ページ数5
ジャーナルMolecular and Cellular Endocrinology
202
1-2
DOI
出版ステータスPublished - 2003 4 28

ASJC Scopus subject areas

  • 生化学
  • 分子生物学
  • 内分泌学

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