Halichonines A, B, and C, novel sesquiterpene alkaloids from the marine sponge Halichondria okadai Kadota

Osamu Ohno, Tatsuhiko Chiba, Seiji Todoroki, Hideaki Yoshimura, Norihito Maru, Ken Maekawa, Hiroshi Imagawa, Kaoru Yamada, Atsushi Wakamiya, Kiyotake Suenaga, Daisuke Uemura

研究成果: Article

13 引用 (Scopus)

抜粋

Novel sesquiterpene alkaloids, halichonines A (1), B (2), and C (3), were identified from the marine sponge Halichondria okadai Kadota. By spectroscopic analyses and synthesis, their structures were revealed to include a 6,6-bicyclic ring system and two prenylated amine moieties. In addition, 2 induced apoptosis in HL60 human leukemia cells.

元の言語English
ページ(範囲)12453-12455
ページ数3
ジャーナルChemical Communications
47
発行部数46
DOI
出版物ステータスPublished - 2011 12 14

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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    Ohno, O., Chiba, T., Todoroki, S., Yoshimura, H., Maru, N., Maekawa, K., Imagawa, H., Yamada, K., Wakamiya, A., Suenaga, K., & Uemura, D. (2011). Halichonines A, B, and C, novel sesquiterpene alkaloids from the marine sponge Halichondria okadai Kadota. Chemical Communications, 47(46), 12453-12455. https://doi.org/10.1039/c1cc15557a