Harnessing human dendritic cell subsets to design novel vaccines

Jacques Banchereau, Eynav Klechevsky, Nathalie Schmitt, Rimpei Morita, Karolina Palucka, Hideki Ueno

研究成果: Article査読

59 被引用数 (Scopus)

抄録

Dendritic cells (DCs) orchestrate a repertoire of immune responses that endow resistance to infection and tolerance to self. DC plasticity and subsets are prominent determinants of the quality of elicited immune responses. Different DC subsets display different receptors and surface molecules and express different sets of cytokines/chemokines, all of which lead to distinct immunological outcomes. Recent findings on human DC subsets and their functional specialization have provided insights for the design of novel human vaccines.

本文言語English
ページ(範囲)24-32
ページ数9
ジャーナルAnnals of the New York Academy of Sciences
1174
DOI
出版ステータスPublished - 2009

ASJC Scopus subject areas

  • Neuroscience(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • History and Philosophy of Science

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