Hepatoprotective activity of phenylethanoids from Cistanche deserticola

Quanbo Xiong, Koji Hase, Yasuhiro Tezuka, Tadato Tani, Tsuneo Namba, Shigetoshi Kadota

研究成果: Article査読

129 被引用数 (Scopus)

抄録

Four phenylethanoids isolated from the stems of Cistanche deserticola, acteoside (1), 2'-acetylacteoside (2), isoacteoside (3) and tubuloside B (4), significantly suppressed NADPH/CCl4-induced lipid peroxidation in rat liver microsomes. Addition of them to primary cultured rat hepatocytes efficiently prevented cell damage induced by exposure to CCl4 or D-galactosamine (D- GalN). Acteoside (1) further showed pronounced anti-hepatotoxic activity against CCl4 in vivo.

本文言語English
ページ(範囲)120-125
ページ数6
ジャーナルPlanta Medica
64
2
出版ステータスPublished - 1998 4 16
外部発表はい

ASJC Scopus subject areas

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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