Four phenylethanoids isolated from the stems of Cistanche deserticola, acteoside (1), 2'-acetylacteoside (2), isoacteoside (3) and tubuloside B (4), significantly suppressed NADPH/CCl4-induced lipid peroxidation in rat liver microsomes. Addition of them to primary cultured rat hepatocytes efficiently prevented cell damage induced by exposure to CCl4 or D-galactosamine (D- GalN). Acteoside (1) further showed pronounced anti-hepatotoxic activity against CCl4 in vivo.
|出版ステータス||Published - 1998 4月 16|
ASJC Scopus subject areas