New hexahydro-dibenz[d,f]azecines, 11 and 12, were synthesized from the homoerythrinan-enone 3. Their 6-oxo derivatives were shown to exist in two conformations in solution due to the rotational isomerism of the ten-membered lactam group. An example of remarkably large separation of two methylenedioxy protons in the proton nuclear magnetic resonance spectrum due to their non-equivalence is also presented.
ASJC Scopus subject areas
- 化学 (全般)