Histological changes in autoimmune hepatitis with graves’ disease: A child case report

Mamiko Yamada, Hironori Shibata, Yohei Masugi, Tomohiro Ishi, Kaori Kameyama, Hirotoshi Ebinuma, Tomonobu Hasegawa

研究成果: Article

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We herein report a child case of autoimmune hepatitis (AIH) accompanied with Graves’ disease. Elevated aminotransferase levels were found in a 12-year-old Japanese girl with Graves’ disease. In her first liver biopsy, necrosis and inflammation was limited to the centrilobular area, while the second biopsy showed different findings. Namely, portal injury newly appeared, including interface hepatitis, which represents the histological characteristics of AIH. As the histological findings at the onset of AIH do not always show typical findings, a re-biopsy is considered to be important in individuals suspected to have AIH. AIH should be included in the differential diagnosis of liver dysfunction in Graves’ disease, even in children.

元の言語English
ページ(範囲)2139-2143
ページ数5
ジャーナルInternal Medicine
56
発行部数16
DOI
出版物ステータスPublished - 2017

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ASJC Scopus subject areas

  • Internal Medicine

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