Hoshinoamides A and B, Acyclic Lipopeptides from the Marine Cyanobacterium Caldora penicillata

Arihiro Iwasaki, Takato Tadenuma, Shimpe Sumimoto, Ikuma Shiota, Teruhiko Matsubara, Yumiko Saito-Nakano, Tomoyoshi Nozaki, Toshinori Sato, Kiyotake Suenaga

研究成果: Article査読

7 被引用数 (Scopus)

抄録

Hoshinoamides A (1) and B (2), new acyclic lipopeptides, were isolated from the marine cyanobacterium Caldora penicillata. Their structures were elucidated by spectroscopic analyses and degradation reactions. Hoshinoamides A (1) and B (2) did not exhibit any cytotoxicity against HeLa cells at 10 μM, but inhibited the in vitro growth of the malarial parasite Plasmodium falciparum (IC50 = 0.52 and 1.0 μM, respectively).

本文言語English
ページ(範囲)2545-2552
ページ数8
ジャーナルJournal of Natural Products
81
11
DOI
出版ステータスPublished - 2018 11 26

ASJC Scopus subject areas

  • 分析化学
  • 分子医療
  • 薬理学
  • 薬科学
  • 創薬
  • 補完代替医療
  • 有機化学

フィンガープリント

「Hoshinoamides A and B, Acyclic Lipopeptides from the Marine Cyanobacterium Caldora penicillata」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル