How do Japanese gynecologists view hormone replacement therapy for survivors of endometrial cancer? Japanese Gynecologic Oncology Group (JGOG) survey

Yoshihito Yokoyama, Kiyoshi Ito, Kiyoshi Takamatsu, Kazuhiro Takehara, Toru Nakanishi, Kenichi Harano, Hidemichi Watari, Nobuyuki Susumu, Daisuke Aoki, Toshiaki Saito

研究成果: Article

4 引用 (Scopus)


Background: This survey sought to determine Japanese gynecologists’ attitudes concerning administering hormone replacement therapy (HRT) for patients after surgery for endometrial cancer (EC). Methods: Eight hundred and eighty-eight members of the Japanese Gynecologic Oncology Group (JGOG) were asked to respond to an anonymous questionnaire on the JGOG website. The survey asked whether or not HRT was to be administered when surgery was performed (including a hysterectomy and bilateral oophorectomy) to treat EC before or after menopause. If HRT was not to be administered, respondents were asked the reason why. Respondents were presented with the same hypothetical patients that were featured in a previous survey in Germany, and differences in the mindsets of Japanese and German physicians were compared. Results: Responses from 363 individuals (response rate 40.9 %) were analyzed. Seventy-eight percent of physicians considered HRT for patients undergoing surgery before menopause. The most prevalent reason of refusal to prescribe HRT was the risk of EC recurrence. Forty-eight percent of physicians considered HRT for patients undergoing surgery after menopause. The most prevalent reasons of refusal of HRT were its limited benefit and the availability of alternative therapies. Sixty-five percent of Japanese physicians responded that they would administer HRT to patients with low risk of recurrence vs. 46 % of physicians in Germany (P 

ジャーナルInternational Journal of Clinical Oncology
出版物ステータスPublished - 2015 10 3


ASJC Scopus subject areas

  • Oncology
  • Surgery
  • Hematology