抄録
To evaluate the accuracy of the human chorionic gonadotropin (hCG) stimulation test in children with micropenis in predicting later Leydig cell function. Methods: We conducted a retrospective investigation of testosterone response to a 3-day hCG test (3,000 IU/m2/day) in prepuberty to indicate the need for hormone replacement therapy (HRT) in adolescence. Results: Fifty Japanese boys (range, 0.8-15.4 years of age; median, 8.9) with micropenis were enrolled. Thirty-four spontaneously developed puberty and preserved the ability of testosterone production (group 1), while 16 did not develop any pubertal signs without HRT (group 2). Serum testosterone levels after the hCG test (post-hCG T) in group 2 (range,
本文言語 | English |
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ページ(範囲) | 305-310 |
ページ数 | 6 |
ジャーナル | Hormone Research in Paediatrics |
巻 | 84 |
号 | 5 |
DOI | |
出版ステータス | Published - 2015 11 1 |
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Endocrinology
- Endocrinology, Diabetes and Metabolism