Human Chorionic Gonadotropin Stimulation Test in Prepubertal Children with Micropenis Can Accurately Predict Leydig Cell Function in Pubertal or Postpubertal Adolescents

Tomohiro Ishii; Nobutake Matsuo; Seiji Sato; Tsutomu Ogata; Shinya Tamai; Makoto Anzo; Tsutomu Kamimaki; Goro Sasaki; Mikako Inokuchi; Naoaki Hori; Naoko Amano; Satoshi Narumi; Hironori Shibata; Tomonobu Hasegawa

doi:10.1159/000439234

Human Chorionic Gonadotropin Stimulation Test in Prepubertal Children with Micropenis Can Accurately Predict Leydig Cell Function in Pubertal or Postpubertal Adolescents

Tomohiro Ishii, Nobutake Matsuo, Seiji Sato, Tsutomu Ogata, Shinya Tamai, Makoto Anzo, Tsutomu Kamimaki, Goro Sasaki, Mikako Inokuchi, Naoaki Hori, Naoko Amano, Satoshi Narumi, Hironori Shibata, Tomonobu Hasegawa

研究成果: Article

5 引用（Scopus）

抜粋

To evaluate the accuracy of the human chorionic gonadotropin (hCG) stimulation test in children with micropenis in predicting later Leydig cell function. Methods: We conducted a retrospective investigation of testosterone response to a 3-day hCG test (3,000 IU/m²/day) in prepuberty to indicate the need for hormone replacement therapy (HRT) in adolescence. Results: Fifty Japanese boys (range, 0.8-15.4 years of age; median, 8.9) with micropenis were enrolled. Thirty-four spontaneously developed puberty and preserved the ability of testosterone production (group 1), while 16 did not develop any pubertal signs without HRT (group 2). Serum testosterone levels after the hCG test (post-hCG T) in group 2 (range,

元の言語	English
ページ（範囲）	305-310
ページ数	6
ジャーナル	Hormone Research in Paediatrics
巻	84
発行部数	5
DOI	https://doi.org/10.1159/000439234
出版物ステータス	Published - 2015 11 1

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Endocrinology
Endocrinology, Diabetes and Metabolism

文献にアクセス

10.1159/000439234

フィンガープリント Human Chorionic Gonadotropin Stimulation Test in Prepubertal Children with Micropenis Can Accurately Predict Leydig Cell Function in Pubertal or Postpubertal Adolescents' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

これを引用

Ishii, T., Matsuo, N., Sato, S., Ogata, T., Tamai, S., Anzo, M., Kamimaki, T., Sasaki, G., Inokuchi, M., Hori, N., Amano, N., Narumi, S., Shibata, H., & Hasegawa, T. (2015). Human Chorionic Gonadotropin Stimulation Test in Prepubertal Children with Micropenis Can Accurately Predict Leydig Cell Function in Pubertal or Postpubertal Adolescents. Hormone Research in Paediatrics, 84(5), 305-310. https://doi.org/10.1159/000439234

Human Chorionic Gonadotropin Stimulation Test in Prepubertal Children with Micropenis Can Accurately Predict Leydig Cell Function in Pubertal or Postpubertal Adolescents. / Ishii, Tomohiro; Matsuo, Nobutake; Sato, Seiji; Ogata, Tsutomu; Tamai, Shinya; Anzo, Makoto; Kamimaki, Tsutomu; Sasaki, Goro; Inokuchi, Mikako; Hori, Naoaki; Amano, Naoko; Narumi, Satoshi; Shibata, Hironori; Hasegawa, Tomonobu.

：: Hormone Research in Paediatrics, 巻 84, 番号 5, 01.11.2015, p. 305-310.

研究成果: Article

Ishii, T, Matsuo, N, Sato, S, Ogata, T, Tamai, S, Anzo, M, Kamimaki, T, Sasaki, G, Inokuchi, M, Hori, N, Amano, N, Narumi, S, Shibata, H & Hasegawa, T 2015, 'Human Chorionic Gonadotropin Stimulation Test in Prepubertal Children with Micropenis Can Accurately Predict Leydig Cell Function in Pubertal or Postpubertal Adolescents', Hormone Research in Paediatrics, 巻. 84, 番号 5, pp. 305-310. https://doi.org/10.1159/000439234

Ishii, Tomohiro ; Matsuo, Nobutake ; Sato, Seiji ; Ogata, Tsutomu ; Tamai, Shinya ; Anzo, Makoto ; Kamimaki, Tsutomu ; Sasaki, Goro ; Inokuchi, Mikako ; Hori, Naoaki ; Amano, Naoko ; Narumi, Satoshi ; Shibata, Hironori ; Hasegawa, Tomonobu. / Human Chorionic Gonadotropin Stimulation Test in Prepubertal Children with Micropenis Can Accurately Predict Leydig Cell Function in Pubertal or Postpubertal Adolescents. ：: Hormone Research in Paediatrics. 2015 ; 巻 84, 番号 5. pp. 305-310.

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abstract = "To evaluate the accuracy of the human chorionic gonadotropin (hCG) stimulation test in children with micropenis in predicting later Leydig cell function. Methods: We conducted a retrospective investigation of testosterone response to a 3-day hCG test (3,000 IU/m2/day) in prepuberty to indicate the need for hormone replacement therapy (HRT) in adolescence. Results: Fifty Japanese boys (range, 0.8-15.4 years of age; median, 8.9) with micropenis were enrolled. Thirty-four spontaneously developed puberty and preserved the ability of testosterone production (group 1), while 16 did not develop any pubertal signs without HRT (group 2). Serum testosterone levels after the hCG test (post-hCG T) in group 2 (range, ",

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AU - Sato, Seiji

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AU - Tamai, Shinya

AU - Anzo, Makoto

AU - Kamimaki, Tsutomu

AU - Sasaki, Goro

AU - Inokuchi, Mikako

AU - Hori, Naoaki

AU - Amano, Naoko

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