Human immunodeficiency virus-reverse transcriptase inhibition and hepatitis C virus RNA-dependent RNA polymerase inhibition activities of fullerene derivatives

Tadahiko Mashino, Kumiko Shimotohno, Noriko Ikegami, Dai Nishikawa, Kensuke Okuda, Kyoko Takahashi, Shigeo Nakamura, Masataka Mochizuki

研究成果: Article

139 引用 (Scopus)

抄録

We examined the human immunodeficiency virus-reverse transcriptase and hepatitis C virus RNA-dependent RNA polymerase inhibition activities of cationic, anionic, and amino acid-type fullerene derivatives. Among the fullerene derivatives, the amino acid-type fullerene derivative was the most efficient in human immunodeficiency virus-reverse transcriptase inhibition.

元の言語English
ページ(範囲)1107-1109
ページ数3
ジャーナルBioorganic and Medicinal Chemistry Letters
15
発行部数4
DOI
出版物ステータスPublished - 2005 2 15

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Fullerenes
HIV Reverse Transcriptase
RNA Replicase
Viruses
Hepacivirus
Derivatives
Amino Acids

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Organic Chemistry
  • Drug Discovery
  • Pharmaceutical Science

これを引用

Human immunodeficiency virus-reverse transcriptase inhibition and hepatitis C virus RNA-dependent RNA polymerase inhibition activities of fullerene derivatives. / Mashino, Tadahiko; Shimotohno, Kumiko; Ikegami, Noriko; Nishikawa, Dai; Okuda, Kensuke; Takahashi, Kyoko; Nakamura, Shigeo; Mochizuki, Masataka.

:: Bioorganic and Medicinal Chemistry Letters, 巻 15, 番号 4, 15.02.2005, p. 1107-1109.

研究成果: Article

Mashino, Tadahiko ; Shimotohno, Kumiko ; Ikegami, Noriko ; Nishikawa, Dai ; Okuda, Kensuke ; Takahashi, Kyoko ; Nakamura, Shigeo ; Mochizuki, Masataka. / Human immunodeficiency virus-reverse transcriptase inhibition and hepatitis C virus RNA-dependent RNA polymerase inhibition activities of fullerene derivatives. :: Bioorganic and Medicinal Chemistry Letters. 2005 ; 巻 15, 番号 4. pp. 1107-1109.
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AU - Nishikawa, Dai

AU - Okuda, Kensuke

AU - Takahashi, Kyoko

AU - Nakamura, Shigeo

AU - Mochizuki, Masataka

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AB - We examined the human immunodeficiency virus-reverse transcriptase and hepatitis C virus RNA-dependent RNA polymerase inhibition activities of cationic, anionic, and amino acid-type fullerene derivatives. Among the fullerene derivatives, the amino acid-type fullerene derivative was the most efficient in human immunodeficiency virus-reverse transcriptase inhibition.

KW - Anti-HCV

KW - Anti-HIV

KW - Fullerene

KW - Reverse transcriptase

KW - RNA-dependent RNA polymerase

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