@article{3dc53e2cfe154339857970df0c82829a,
title = "Hyaluronan Degradation by Cemip Regulates Host Defense against Staphylococcus aureus Skin Infection",
abstract = "In this paper, Dokoshi et al. describe how the mammalian hyaluronidase Cemip is induced in the dermis during S. aureus infection. Cemip digests hyaluronan in the skin to regulate reactive adipogenesis and subsequent antimicrobial activity and skin inflammation.",
keywords = "Staphylococcus aureus, antimicrobial peptides, cathelicidin, dermis, glycosaminoglycans, hyaluronan, innate immunity, skin",
author = "Tatsuya Dokoshi and Zhang, {Ling juan} and Fengwu Li and Teruaki Nakatsuji and Anna Butcher and Hiroyuki Yoshida and Masayuki Shimoda and Yasunori Okada and Gallo, {Richard L.}",
note = "Funding Information: T.D. and R.L.G. were funded by NIH grant P01HL107150 . L.Z., T.N., and R.L.G. are funded by NIH grants R01AR069653 and R37AI052453 . Funding Information: T.D. and R.L.G. were funded by NIH grant P01HL107150. L.Z. T.N. and R.L.G. are funded by NIH grants R01AR069653 and R37AI052453. T.D. and R.L.G. designed and performed experiments, analyzed data, and wrote the paper. F.L. designed and performed experiments and analyzed data. H.Y. designed experiments and analyzed data. M.S. and Y.O. provided Cemip?/? mice. H.Y. is an employee of Kao Corporation (Odawara-shi, Kanagawa, Japan). R.L.G. is a co-founder, a scientific adviser, a consultant, and an equity holder in MatriSys Biosciences and is a consultant for, receives income from, and has equity in Sente. Publisher Copyright: {\textcopyright} 2019 The Authors",
year = "2020",
month = jan,
day = "7",
doi = "10.1016/j.celrep.2019.12.001",
language = "English",
volume = "30",
pages = "61--68.e4",
journal = "Cell Reports",
issn = "2211-1247",
publisher = "Cell Press",
number = "1",
}